4-异丙氧基-4-氧代丁酸合成路线 （共 7 条）
反应条件
toluene-4-sulfonic acid in toluene 24 h; Inert atmosphereReflux;
参考文献
Iqbal, Muhammad; Baloch, Imam Bakhsh; Baloch, Musa Kaleem
Asian Journal of Chemistry, 2013 , vol. 25, # 17 p. 9701 - 9703
反应条件
hydrogen; 5 Pd(II)/C(eggshell) T=80°C; P=4897.99 Torr; 18 h; Sealed; Product distribution / selectivity;
参考文献
INVISTA TECHNOLOGIES S.A. R.L.; SUN, Yanhui; BEATTY, Richard, P.
Patent: WO2011/17543 A1, 2011 ;
Location in patent: Page/Page column 18 ;
参考文献
Yan, Jun; Travis, Benjamin R.; Borhan, Babak
Journal of Organic Chemistry, 2004 , vol. 69, # 26 p. 9299 - 9302
参考文献
Yan, Jun; Travis, Benjamin R.; Borhan, Babak
Journal of Organic Chemistry, 2004 , vol. 69, # 26 p. 9299 - 9302
参考文献
Veibel; Pedersen
Acta Chemica Scandinavica (1947-1973), 1955 , vol. 9, p. 1674,1678
反应条件
1: With xylene sulfonic acid catalyst T=110°C; 2: With potassium hydroxide
参考文献
INVISTA TECHNOLOGIES S.A. R.L.; SUN, Yanhui; BEATTY, Richard, P.
Patent: WO2011/17543 A1, 2011 ;
Location in patent: Page/Page column 20 ;
反应条件
1: oxalyl chloride / benzene; dimethylformamide / 6 h / 20 °C
2: 4.03 g / hydrogen; 2,6-lutidine / Pd/C / tetrahydrofuran / 12 h
View Scheme
参考文献
Dos Santos, Alcindo A.; Francke, Wittko
Tetrahedron Asymmetry, 2006 , vol. 17, # 17 p. 2487 - 2490
