4-溴-4'-(二苯氨基)联苯合成路线 （共 10 条）
反应条件
1,1'-bis(diphenylphosphino)ferrocene; palladium diacetate; sodium t-butanolate in toluene T=90°C; Buchwald-Hartwig coupling; 15 h; Inert atmosphere;
参考文献
Chang, Yuan Jay; Chow, Tahsin J.
Tetrahedron, 2009 , vol. 65, # 24 p. 4726 - 4734
参考文献
Palsson, Lars-Olof; Wang, Changsheng; Batsanov, Andrei S.; King, Simon M.; Beeby, Andrew; Monkman, Andrew P.; Bryce, Martin R.
Chemistry - A European Journal, 2010 , vol. 16, # 5 p. 1470 - 1479
反应条件
sodium carbonate; Pd(PPh3)4 in tetrahydrofuran-water
参考文献
NITTO DENKO CORPORATION; ZHENG, Shijun; CAYAS, Jensen; LI, Sheng; MOCHIZUKI, Amane; CHAF, Hyunsik; HARDING, Brett, T.
Patent: WO2011/8560 A1, 2011 ;
Location in patent: Page/Page column 47-48 ;
反应条件
tetrakis(triphenylphosphine) palladium(0); sodium carbonate in tetrahydrofuran; water; toluene Suzuki Coupling; 24 h; RefluxInert atmosphere;
参考文献
Ci, Zhenhua; Yu, Xiaoqiang; Bao, Ming; Wang, Chaolei; Ma, Tingli
Dyes and Pigments, 2013 , vol. 96, # 3 p. 619 - 625
反应条件
1: iodine; periodic acid dihydrate / sulfuric acid / acetic acid / 6.5 h / 65 - 90 °C 2: sodium t-butanolate / bis-triphenylphosphine-palladium(II) chloride / xylene / 24 h / 130 °C / Inert atmosphere View Scheme
反应条件
1.1: n-butyllithium / tetrahydrofuran; hexanes / 5 h / -78 °C 1.2: 20 °C 2.1: sodium carbonate / tetrakis(triphenylphosphine) palladium(0) / water; tetrahydrofuran / Inert atmosphere; Reflux View Scheme
反应条件
1,1'-bis-(diphenylphosphino)ferrocene; sodium t-butanolate; tris(dibenzylideneacetone)dipalladium (0) in toluene T=100°C; 6 h;
参考文献
Bacher, Erwin; Bayerl, Michael; Rudati, Paula; Reckefuss, Nina; Mueller, C.David; Meerholz, Klaus; Nuyken, Oskar
Macromolecules, 2005 , vol. 38, # 5 p. 1640 - 1647
参考文献
Idemitsu Kosan Co., Ltd.
Patent: US2006/232198 A1, 2006 ;
反应条件
1: With n-butyllithium in tetrahydrofuran
1 h; cooling;
2: With boric acid trimethyl ester in tetrahydrofuran
2 h; cooling;
3: With hydrogenchloride in tetrahydrofuran; water
参考文献
Li, Zhong Hui; Wong, Man Shing; Tao, Ye; D'Iorio, Marie
Journal of Organic Chemistry, 2004 , vol. 69, # 3 p. 921 - 927
反应条件
1.1: n-BuLi / tetrahydrofuran / 1 h / cooling
1.2: trimethyl borate / tetrahydrofuran / 2 h / cooling
1.3: 77 percent / HCl / tetrahydrofuran; H2O
2.1: 89 percent / Pd(PPh3)4; K2CO3 / tetrahydrofuran / 50 °C
View Scheme
参考文献
Li, Zhong Hui; Wong, Man Shing; Tao, Ye; D'Iorio, Marie
Journal of Organic Chemistry, 2004 , vol. 69, # 3 p. 921 - 927
