2-溴-4,6-二氟苯甲醚合成路线 (共 3 条)
反应条件
1: With n-butyllithium in tetrahydrofuran T=-78°C; 0.333333 h; 2: With tri-isopropoxy-borane in tetrahydrofuran T=-78°C; 1 h; 3: With hydrogenchloride in tetrahydrofuran T=-78 - 20°C; Further stages.;
参考文献
Jones, Lyn H.; Randall, Amy; Barba, Oscar; Selby, Matthew D.
Organic and Biomolecular Chemistry, 2007 , vol. 5, # 21 p. 3431 - 3433
反应条件
hydrogenchloride; n-butyllithium in tetrahydrofuran reacting aryl bromide with n-butyllithium in THF at -78°C, addn. of boron compd., reaction with aq. HCl;
参考文献
Jones, Lyn H.; Randall, Amy; Barba, Oscar; Selby, Matthew D.
Organic and Biomolecular Chemistry, 2007 , vol. 5, # 21 p. 3431 - 3433
反应条件
1: With n-butyllithium in tetrahydrofuran; diethyl ether T=-78°C; 0.0333333 h; 2: With tri-isopropoxy-borane in tetrahydrofuran; diethyl ether T=-78 - 20°C; 3: With hydrogenchloride in tetrahydrofuran; diethyl ether 0.5 h; Further stages.;
参考文献
Jones, Lyn H.; Randall, Amy; Barba, Oscar; Selby, Matthew D.
Organic and Biomolecular Chemistry, 2007 , vol. 5, # 21 p. 3431 - 3433