2-(2-(4-氯苯基)噻唑-4-基)乙酸乙酯合成路线 （共 3 条）
反应条件
in ethanol 2 h; Heating / reflux;
参考文献
WO2006/66174 A1, ;
Page/Page column 38 ;
WO 2006/066174 A1
反应条件
pyridine 6 h; Heating;
参考文献
Collection of Czechoslovak Chemical Communications, , vol. 66, # 12 p. 1809 - 1830
反应条件
1: With diisobutylaluminium hydride in tetrahydrofuran
T=0 - 20°C;
2: With water; Potassium sodium tartrate in tetrahydrofuran
T=0 - 10°C; 5 h;
参考文献
ELI LILLY AND COMPANY
Patent: WO2008/76562 A1, 2008 ;
Location in patent: Page/Page column 22-23 ;
WO 2008/076562 A1
