1-甲基-1H-1,2,3-噻唑-5-甲醛合成路线 (共 2 条)
反应条件
1: 3MeTA With n-butyllithium in tetrahydrofuran T=-78 - -60°C; 0.5 h; 2: N,N-dimethyl-formamide in tetrahydrofuran T=20°C; 1 h;
参考文献
PFIZER LIMITED
Patent: WO2008/135826 A2, 2008 ;
Location in patent: Page/Page column 157; 158 ;
WO 2008/135826 A2
反应条件
n-butyllithium in N,N-dimethyl-formamide
参考文献
Merck Sharp and Dohme Limited
Patent: US6255305 B1, 2001 ;
US 6255305 B1