反应条件
1: 42 h / Ambient temperature
2: HCl(g) / acetonitrile / 20 h / -42 - 20 °C
3: 1,8-diazabicyclo<5.4.0>undec-7-ene / benzene / Ambient temperature
4: BF3*Et2O / benzene; methanol / 18 h / Ambient temperature
View Scheme
参考文献
CATABASIS PHARMACEUTICALS, INC.; MILNE, Jill C.; JIROUSEK, Michael R.; VU, Chi B.; WENSLEY, Allison; TING, Amal
Patent: WO2013/90420 A2, 2013 ;