反应条件
1: 1.) n-BuLi / 1.) Et2O, hexane, 2 h, 2.) Et2O, overnight
2: 73 percent / Dess-Martin reagent / CH2Cl2 / 0.5 h / Ambient temperature
3: 1.) polyphosphoric acid (PPA), 2.) 2,3-dichloro-5,6-dicyano-1,4-benzoquinone (DDQ) / 1.) 110 deg C, 2 h, 2.) benzene, reflux, 30 min
View Scheme
参考文献
Cho, Bongsup P.; Harvey, Ronald G.
Journal of Organic Chemistry, 1987 , vol. 52, # 26 p. 5668 - 5678
