1-氧代-2-甲基-6,7-二甲氧基-1,2-二氢异喹啉合成路线 （共 25 条）
反应条件
1: acetonitrile / 2 h / 80 °C
2: 1) AgCl, 2) rat liver enzymes / 1) methanol, 2) 37 deg C, 2 h, pH 7.5
View Scheme
参考文献
Walterova; Preininger; Dolejs; et al.
Collection of Czechoslovak Chemical Communications, 1980 , vol. 45, # 3 p. 956 - 965
反应条件
1: 6 h / Ambient temperature; alternative: 3 h heating on a boiling water-bath
2: 0.34 g / SeO2 / dioxane / 9 h / Heating
3: 30percent aq. NaOH / 1 h
4: 0.33 h / 300 - 310 °C
View Scheme
参考文献
Modi, A. R.; Tirodkar, R. B.; Usgaonkar, R. N.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1981 , vol. <B> 20, # 9 p. 813 - 815
反应条件
1: 6 h / Ambient temperature; alternative: 3 h heating on a boiling water-bath
2: 0.34 g / SeO2 / dioxane / 9 h / Heating
3: 30percent aq. NaOH / 1 h
4: 0.33 h / 300 - 310 °C
View Scheme
参考文献
Modi, A. R.; Tirodkar, R. B.; Usgaonkar, R. N.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1981 , vol. <B> 20, # 9 p. 813 - 815
反应条件
1: 6 h / Ambient temperature; alternative: 3 h heating on a boiling water-bath
2: 0.34 g / SeO2 / dioxane / 9 h / Heating
3: 30percent aq. NaOH / 1 h
4: 0.33 h / 300 - 310 °C
View Scheme
参考文献
Modi, A. R.; Tirodkar, R. B.; Usgaonkar, R. N.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1981 , vol. <B> 20, # 9 p. 813 - 815
反应条件
1: 1. pyridine/CHCl3/room temperature/45 min 2. heating on a boling water-bath/2 h
2: 0.34 g / SeO2 / dioxane / 9 h / Heating
3: 30percent aq. NaOH / 1 h
4: 0.33 h / 300 - 310 °C
View Scheme
参考文献
Modi, A. R.; Tirodkar, R. B.; Usgaonkar, R. N.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1981 , vol. <B> 20, # 9 p. 813 - 815
反应条件
1: 0.34 g / SeO2 / dioxane / 9 h / Heating
2: 30percent aq. NaOH / 1 h
3: 0.33 h / 300 - 310 °C
View Scheme
参考文献
Modi, A. R.; Tirodkar, R. B.; Usgaonkar, R. N.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1981 , vol. <B> 20, # 9 p. 813 - 815
反应条件
sodium tetrahydroborate; Fremy’s salt; anhydrous carbonate
1.)ethanol, water, 24 h; Multistep reaction;
参考文献
Castedo, Luis; Puga, Alberto; Saa, Jose M.; Suau, Rafael
Tetrahedron Letters, 1981 , vol. 22, # 23 p. 2233 - 2236
反应条件
1: 52 percent / 120 h / 170 °C
2: 21 percent / o-xylene / 72 h / 180 °C
View Scheme
参考文献
Fujita; Hoshino; Tomisawa; Hongo
Chemical and Pharmaceutical Bulletin, 2000 , vol. 48, # 11 p. 1814 - 1817
反应条件
1: 52 percent / 120 h / 170 °C
2: 21 percent / o-xylene / 72 h / 180 °C
View Scheme
参考文献
Fujita; Hoshino; Tomisawa; Hongo
Chemical and Pharmaceutical Bulletin, 2000 , vol. 48, # 11 p. 1814 - 1817
反应条件
T=300 - 310°C; 0.333333 h;
参考文献
Modi, A. R.; Tirodkar, R. B.; Usgaonkar, R. N.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1981 , vol. <B> 20, # 9 p. 813 - 815
