米氏酸合成路线 - 魔法化学

参考文献

NIHON NOHYAKU CO., LTD.
Patent: EP1852428 A1, 2007 ;
Location in patent: Page/Page column 31 ;

2033-24-1米氏酸+

4023-34-1环丙基甲酰氯

32249-35-73-环丙基-3-氧代丙酸甲酯

参考文献

ABBOTT GMBH and CO. KG
Patent: WO2006/15842 A1, 2006 ;
Location in patent: Page/Page column 36 ;
WO 2006/015842 A1

104-53-0苯丙醛+

2033-24-1米氏酸

2270-20-45-苯基戊酸

参考文献

Mudhar, Harminder; Witty, Andrew
Tetrahedron Letters, 2010 , vol. 51, # 38 p. 4972 - 4974

2033-24-1米氏酸+

112-13-0癸酰氯

22348-96-53-氧代癸酸甲酯

参考文献

Kwan, Eugene E.; Scheerer, Onathan R.; Evans, David A.
Journal of Organic Chemistry, 2013 , vol. 78, # 1 p. 175 - 203

2033-24-1米氏酸+

64-17-5乙醇+

89186-79-8乙酰氯-13C2

89186-80-1乙酰乙酸乙酯-3,4-13C2

参考文献

Townsend, Craig A.; Christensen, Siegfried B.; Davis, Steven G.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1988 , p. 839 - 862

2033-24-1米氏酸+

367-25-92,4-二氟苯胺

243448-16-06,8-二氟-4-羟基喹啉

参考文献

Margolis, Brandon J.; Long, Kimberly A.; Laird, Dana L. T.; Ruble, J. Craig; Pulley, Shon R.
Journal of Organic Chemistry, 2007 , vol. 72, # 6 p. 2232 - 2235

参考文献

Blackburn, Tim J.; Ahmed, Shafiq; Coxon, Christopher R.; Liu, Junfeng; Lu, Xiaohong; Golding, Bernard T.; Griffin, Roger J.; Hutton, Claire; Newell, David R.; Ojo, Stephen; Watson, Anna F.; Zaytzev, Andrey; Zhao, Yan; Lunec, John; Hardcastle, Ian R.
MedChemComm, 2013 , vol. 4, # 9 p. 1297 - 1304

2033-24-1米氏酸+

529-23-72-氨基苯甲醛

2003-79-42-羟基-3-喹啉羧酸

参考文献

Pathuri, Gopal; Li, Qian; Mohammed, Altaf; Gali, Hariprasad; Pento, J. Thomas; Rao, Chinthalapally V.
Bioorganic and Medicinal Chemistry Letters, 2014 , vol. 24, # 5 p. 1380 - 1382

2033-24-1米氏酸+

124-13-0正辛醛

334-48-5正癸酸

参考文献

Mudhar, Harminder; Witty, Andrew
Tetrahedron Letters, 2010 , vol. 51, # 38 p. 4972 - 4974

2033-24-1米氏酸+

659-28-9

886499-74-7

参考文献

Englert; Gerlach; Goegelein; Hartung; Heitsch; Mania; Scheidler
Journal of Medicinal Chemistry, 2001 , vol. 44, # 7 p. 1085 - 1098