米氏酸合成路线 - 魔法化学

参考文献

Storgaard, Morten; Doerwald, Florencio Zaragoza; Peschke, Bernd; Tanner, David
Journal of Organic Chemistry, 2009 , vol. 74, # 14 p. 5032 - 5040

4530-20-5BOC-甘氨酸+

2033-24-1米氏酸+

108-23-6氯甲酸异丙酯

182352-48-32,5-二氢-4-羟基-2-氧代-1H-吡咯-1-甲酸叔丁酯

参考文献

Yoon-Miller, Sarah J.P.; Opalka, Suzanne M.; Pelkey, Erin T.
Tetrahedron Letters, 2007 , vol. 48, # 5 p. 827 - 830

2033-24-1米氏酸+

67-64-1丙酮

2231-66-52,2-二甲基-5-(1-甲基亚乙基)-1,3-二噁烷-4,6-二酮

参考文献

BOEHRINGER INGELHEIM INTERNATIONAL GMBH; FANDRICK, Daniel Robert; YEE, Nathan; SONG, Jinhua J.; REEVES, Jonathan Timothy
Patent: WO2010/141334 A1, 2010 ;
Location in patent: Page/Page column 13-14 ;

2033-24-1米氏酸

参考文献

Ratiopharm GmbH
Patent: EP1705175 A1, 2006 ;
Location in patent: Page/Page column 5; 17 ;

2033-24-1米氏酸+

109-49-95-已烯-2-酮

2231-66-52,2-二甲基-5-(1-甲基亚乙基)-1,3-二噁烷-4,6-二酮

参考文献

Snider, Barry B.; Smith, Rachel B.
Tetrahedron, 2002 , vol. 58, # 1 p. 25 - 34

2033-24-1米氏酸+

75-65-0叔丁醇

2231-66-52,2-二甲基-5-(1-甲基亚乙基)-1,3-二噁烷-4,6-二酮+

40052-13-9丙二酸单叔丁酯

参考文献

Ratiopharm GmbH
Patent: EP1834944 A1, 2007 ;
Location in patent: Page/Page column 5 ;

2033-24-1米氏酸

2231-66-52,2-二甲基-5-(1-甲基亚乙基)-1,3-二噁烷-4,6-二酮

参考文献

Tararov, Vitali I.; Korostylev, Andrei; Koenig, Gerd; Boerner, Armin
Synthetic Communications, 2006 , vol. 36, # 2 p. 187 - 191

参考文献

Rigo, B.; Fasseur, D.; Cauliez, P.; Couturier, D.
Tetrahedron Letters, 1989 , vol. 30, # 23 p. 3073 - 3076

2033-24-1米氏酸+

1761-61-15-溴水杨醛

2199-87-36-溴香豆素-3-甲酸

参考文献

Hekmatshoar, Rahim; Rezaei, Akram; Beheshtiha, S. Y. Shirazi
Phosphorus, Sulfur and Silicon and the Related Elements, 2009 , vol. 184, # 9 p. 2491 - 2496

2033-24-1米氏酸+

75-36-5乙酰氯

72324-39-15-乙酰基-2,2-二甲基-1,3-二恶烷-4,6-二酮

参考文献

More; Mahulikar
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2006 , vol. 45, # 3 p. 823 - 825