3-溴-2-氯-6-氟甲苯合成路线 （共 4 条）
反应条件
bromine; iron 0.25 h;
参考文献
Schlienger, Nathalie; Thygesen, Mikkel Boas; Pawlas, Jan; Badalassi, Fabrizio; Lewinsky, Rasmus; Lund, Birgitte Winther; Olsson, Roger
Patent: US2006/160845 A1, 2006 ;
Location in patent: Page/Page column 18 ;
反应条件
bromine; iron T=20°C;
参考文献
Journal of Medicinal Chemistry, , vol. 52, # 22 p. 7186 - 7191
反应条件
tetrakis(triphenylphosphine) palladium(0) in N,N-dimethyl-formamide T=120°C; 2 h; Product distribution / selectivity;
参考文献
Schlienger, Nathalie; Thygesen, Mikkel Boas; Pawlas, Jan; Badalassi, Fabrizio; Lewinsky, Rasmus; Lund, Birgitte Winther; Olsson, Roger
Patent: US2006/160845 A1, 2006 ;
Location in patent: Page/Page column 19 ;
反应条件
tetrakis(triphenylphosphine) palladium(0) in N,N-dimethyl-formamide T=200°C; 0.0416667 h; Microwave irradiation;
参考文献
Schlienger, Nathalie; Lund, Birgitte W.; Pawlas, Jan; Badalassi, Fabrizio; Bertozzi, Fabio; Lewinsky, Rasmus; Fejzic, Alma; Thygesen, Mikkel B.; Tabatabaei, Ali; Bradley, Stefania Risso; Gardell, Luis R.; Piu, Fabrice; Olsson, Roger
Journal of Medicinal Chemistry, 2009 , vol. 52, # 22 p. 7186 - 7191
