2-对甲苯磺酰基-1,2,3,4-四氢异喹啉合成路线 （共 19 条）
反应条件
N,N,N',N'-tetramethyl-7,8-dihydro-6H-dipyrido[1,2-a;2',1'-c][1,4] diazepine-2,12-diamine in N,N-dimethyl-formamide T=20°C; 72 h; UV-irradiation;
参考文献
O'Sullivan, Steven; Doni, Eswararao; Tuttle, Tell; Murphy, John A.
Angewandte Chemie - International Edition, 2014 , vol. 53, # 2 p. 474 - 478
Angew. Chem., 2013 , vol. 126, # 2 p. 484 - 488,5
反应条件
triethylamine in tetrahydrofuran
T=20°C; 10 h;
参考文献
QUEEN'S UNIVERSITY AT KINGSTON
Patent: WO2008/58402 A1, 2008 ;
Location in patent: Page/Page column 101-102 ;
反应条件
diisobutylaluminium hydride; triphenylphosphine; bis(acetylacetonate)nickel(II) in tetrahydrofuran
T=23°C; 18 h;
参考文献
Sato, Yoshihiro; Nishimata, Toyoki; Mori, Miwako
Heterocycles, 1997 , vol. 44, # 1 p. 443 - 457
反应条件
dodeca-tungstophosphoric acid hydrate in acetonitrile
Pictet-Spengler Synthesis; 3 h; RefluxGreen chemistry;
参考文献
Pingaew, Ratchanok; Prachayasittikul, Supaluk; Ruchirawat, Somsak; Prachayasittikul, Virapong
Chinese Chemical Letters, 2013 , vol. 24, # 10 p. 941 - 944
反应条件
potassium carbonate
T=160°C;
参考文献
Holliman; Mann
Journal of the American Chemical Society, 1942 , p. 737,739
反应条件
boron trifluoride diethyl etherate in chloroform; water
0.25 h; Ambient temperature;
参考文献
Orazi, Orfeo O.; Corral, Renee A.; Giaccio, Hector
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1986 , p. 1977 - 1982
反应条件
in chloroform-d1
T=30°C; 36 h;
参考文献
Shain, Jagadish Chandra; Khamrai, Uttam Kumar; Basak, Amit
Tetrahedron Letters, 1997 , vol. 38, # 34 p. 6067 - 6070
反应条件
1: 55 percent / Pd(PPh3)4, n-BuNH2, CuI / benzene / 45 °C
2: CsF / methanol
3: Et3N
4: 85 percent / K2CO3 / dimethylformamide / Ambient temperature
5: CDCl3 / 36 h / 30 °C
View Scheme
参考文献
Shain, Jagadish Chandra; Khamrai, Uttam Kumar; Basak, Amit
Tetrahedron Letters, 1997 , vol. 38, # 34 p. 6067 - 6070
反应条件
1: Et3N
2: 85 percent / K2CO3 / dimethylformamide / Ambient temperature
3: CDCl3 / 36 h / 30 °C
View Scheme
参考文献
Shain, Jagadish Chandra; Khamrai, Uttam Kumar; Basak, Amit
Tetrahedron Letters, 1997 , vol. 38, # 34 p. 6067 - 6070
反应条件
1: CsF / methanol
2: Et3N
3: 85 percent / K2CO3 / dimethylformamide / Ambient temperature
4: CDCl3 / 36 h / 30 °C
View Scheme
参考文献
Shain, Jagadish Chandra; Khamrai, Uttam Kumar; Basak, Amit
Tetrahedron Letters, 1997 , vol. 38, # 34 p. 6067 - 6070
