tetrabutyl ammonium fluoride in tetrahydrofuran; diethyl ether 0.166667 h; Ambient temperature;

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '472690', constants.ctx, '0')">toluene-4-sulfonic acid</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '969212', constants.ctx, '0')">benzene</a> <br />T=90&deg;C;&nbsp;1&nbsp;h;&nbsp;<br /> &nbsp;

<b>Multi-step reaction with 3 steps<br /> </b>1: 96 percent / imidazole / dimethylformamide<br />2: lithium aluminum hydride / diethyl ether; tetrahydrofuran / 2 h / -78 - 20 &deg;C<br />3: Et₃N, methanesulfonyl chloride / CH₂Cl₂ / 24 h / Ambient temperature<br /> <br /> &nbsp;