4-(哌啶-4-羰基)-哌嗪-1-羧酸叔丁酯合成路线 （共 3 条）
反应条件
hydrogen; palladium on activated charcoal in ethanol
18 h;
参考文献
Brown; Hollinshead; Stokes; Waterson; Clarke; Foubister; Glossop; McTaggart; Mirrlees; Smith; Wood
Journal of Medicinal Chemistry, 2000 , vol. 43, # 26 p. 4964 - 4972
反应条件
1: 44 percent / Na2CO3 / H2O / 18 h
2: 76 percent / EDAC; HOBt / dimethylformamide / 18 h
3: 71 percent / H2 / 5 percent Pd/C / ethanol / 18 h
View Scheme
参考文献
Brown; Hollinshead; Stokes; Waterson; Clarke; Foubister; Glossop; McTaggart; Mirrlees; Smith; Wood
Journal of Medicinal Chemistry, 2000 , vol. 43, # 26 p. 4964 - 4972
反应条件
1: 76 percent / EDAC; HOBt / dimethylformamide / 18 h
2: 71 percent / H2 / 5 percent Pd/C / ethanol / 18 h
View Scheme
参考文献
Brown; Hollinshead; Stokes; Waterson; Clarke; Foubister; Glossop; McTaggart; Mirrlees; Smith; Wood
Journal of Medicinal Chemistry, 2000 , vol. 43, # 26 p. 4964 - 4972
