3-(1H-吲哚-3-基)-3-氧丙腈合成路线 （共 9 条）
反应条件
1: anhydrous cyanoacetic acid With acetic anhydride T=85°C; 0.166667 h; 2: indole 0.5 h; Heating; Further stages.;
参考文献
Abdel-Motaleb, Ramadan Maawad; Makhloof, Abdel-Moneim Abdel-Salam; Ibrahim, Hamada Mohamed; Elnagdi, Mohamed Hilmy
Journal of Heterocyclic Chemistry, 2007 , vol. 44, # 1 p. 109 - 114
反应条件
Methanesulfonyl chloride in acetonitrile 1 h; Ambient temperature;
参考文献
Kreher, Richard; Wagner, Paul-Heinz
Chemische Berichte, 1980 , vol. 113, # 11 p. 3675 - 3677
反应条件
in water; benzene T=50°C; 1 h;
参考文献
Journal of Heterocyclic Chemistry, , vol. 44, # 1 p. 109 - 114
反应条件
sodium hydroxide in water 3.5 h; Reflux;
参考文献
Venkatanarayana; Dubey, Pramod K.
Letters in Organic Chemistry, 2011 , vol. 8, # 9 p. 656 - 662
反应条件
1: sodium hydroxide / water / 3.5 h / Reflux 2: tetrabutylammomium bromide; potassium carbonate / acetonitrile / 0.33 h / 20 °C View Scheme
参考文献
Letters in Organic Chemistry, , vol. 8, # 9 p. 656 - 662
反应条件
1: sodium hydroxide / water / 3.5 h / Reflux
2: tetrabutylammomium bromide; potassium carbonate / acetonitrile / 0.47 h / 20 °C
View Scheme
参考文献
Venkatanarayana; Dubey, Pramod K.
Letters in Organic Chemistry, 2011 , vol. 8, # 9 p. 656 - 662
反应条件
1: 84.5 percent / toluene / 0.25 h / 120 °C
2: 71.4 percent / anhydrous potassium carbonate / ethanol / 12 h / Heating
View Scheme
参考文献
Oliveira-Campos, Ana M. F.; Salaheldin, Abdellatif M.; Paz, Filipe A. Almeida; Rodrigues, Ligia M.
Arkivoc, 2011 , vol. 2011, # 11 p. 121 - 133
反应条件
1: sodium hydroxide / water / 3.5 h / Reflux
2: tetrabutylammomium bromide; potassium carbonate / acetonitrile / 0.5 h / 20 °C
View Scheme
参考文献
Venkatanarayana; Dubey, Pramod K.
Letters in Organic Chemistry, 2011 , vol. 8, # 9 p. 656 - 662
反应条件
1: sodium hydroxide / water / 3.5 h / Reflux
2: tetrabutylammomium bromide; potassium carbonate / acetonitrile / 0.3 h / 20 °C
View Scheme
参考文献
Venkatanarayana; Dubey, Pramod K.
Letters in Organic Chemistry, 2011 , vol. 8, # 9 p. 656 - 662
