5-甲氧基-2-硝基苯甲醛合成路线 （共 41 条）
反应条件
potassium carbonate in DMF (N,N-dimethyl-formamide) T=20°C; 16 h;
参考文献
Ramurthy, Savithri; Costales, Abran; Jansen, Johanna M.; Levine, Barry; Renhowe, Paul A.; Shafer, Cynthia M.; Subramanian, Sharadha
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 4 p. 1678 - 1681
反应条件
Dess-Martin periodane in dichloromethane T=20°C; 3 h;
参考文献
SB PHARMCO PUERTO RICO INC; NEUROCRINE BIOSCIENCES INC; GLAXO GROUP LIMITED
Patent: WO2004/62665 A1, 2004 ;
Location in patent: Page/Page column 37 ;
WO 2004/062665 A1
反应条件
sodium hydroxide in water T=40°C; pH=9 - 10; 5 h;
参考文献
Xiong, Xiao-Dong; Chen, Wen-Xue; Kuang, Yun-Yan; Chen, Fen-Er
Organic Preparations and Procedures International, 2009 , vol. 41, # 5 p. 423 - 427
反应条件
potassium carbonate in N,N-dimethyl-formamide T=80°C; 4 h;
参考文献
Gavara, Laurent; Boisse, Thomas; Henichart, Jean-Pierre; Daich, Adam; Rigo, Benoit; Gautret, Philippe
Tetrahedron, 2010 , vol. 66, # 38 p. 7544 - 7561
反应条件
potassium carbonate in ethyl acetate; N,N-dimethyl-formamide
参考文献
US2014/100195 A1, ;
Page/Page column ;
反应条件
1: BH3 / tetrahydrofuran / 3 h / Heating 2: pyridinium dichromate; molecular sieves / CH2Cl2 / 16 h / 20 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 49, # 21 p. 6412 - 6415
反应条件
nitric acid T=0 - 10°C; Aus Benzol krystallisiert 2-Nitro-3-methoxy-benzaldehyd aus; die beiden anderen Isomeren koennen nach Entfernung des Benzols durch Destillation mit Wasserdampf getrennt werden;
参考文献
DE18016 ;
Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 1, p. 586,587
DE20116 ;
Chemische Berichte, , vol. 22, p. 2341
Chemische Berichte, , vol. 18, p. 2572
Chemische Berichte, , vol. 22, p. 2354
反应条件
1: 3.05 g / sodium borohydride / dimethylformamide; tetrahydrofuran / 3 h / 20 °C 2: 88 percent / pyridinium chlorochromate / CH2Cl2 / 2 h / 20 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 12, # 9 p. 2397 - 2407
反应条件
1: nitric acid 2: Durch Methylierung View Scheme
参考文献
Chemische Berichte, , vol. 15, p. 2055
反应条件
sodium hydride; Spirolt;cyclohexan-1,3'-oxaziridingt; 1) DMF, 15 min 2) toluene, 15 min; Yield given. Multistep reaction;
参考文献
Liebigs Annalen der Chemie, , # 6 p. 537 - 538
