toluene-4-sulfonic acid in benzene 6 h; Heating;

1: N-bromosuccinimide / CCl4 / 18 h / Heating 2: acetic acid / 2 h / Heating 3: 98 percent / p-toluenesulfonic acid monohydrate / benzene / 6 h / Heating View Scheme

1: 71 percent / tBuONa; Pd2(dba)3; (S)-(-)-2,2'-bis(diphenylphosphino)-1,1'-binaphthyl / toluene / 40 h / 100 °C 2: 93 percent / p-toluenesulfonic acid / acetone; H2O / 3 h / Heating View Scheme