4,4-二甲基-1,2,3,4-四氢喹啉合成路线

20364-31-24,4-二甲基-1,2,3,4-四氢喹啉

873056-12-37-氨基-4,4-二甲基-3,4-二氢-2H-喹啉-1-羧酸叔丁酯

参考文献

Vertex Pharmaceuticals Incorported
Patent: US2011/98311 A1, 2011 ;

20364-31-24,4-二甲基-1,2,3,4-四氢喹啉

参考文献

Parmenon, Cecile; Guillard, Jerome; Caignard, Daniel-Henri; Hennuyer, Nathalie; Staels, Bart; Audinot-Bouchez, Valerie; Boutin, Jean-Albert; Dacquet, Catherine; Ktorza, Alain; Viaud-Massuard, Marie-Claude
Bioorganic and Medicinal Chemistry Letters, 2008 , vol. 18, # 5 p. 1617 - 1622

13209-80-8

20364-31-24,4-二甲基-1,2,3,4-四氢喹啉

参考文献

Higuchi, Robert I.; Edwards, James P.; Caferro, Thomas R.; Ringgenberg, Josef D.; Kong, James W.; Hamann, Lawrence G.; Arienti, Kristen L.; Marschke, Keith B.; Davis, Robert L.; Farmer, Luc J.; Jones, Todd K.
Bioorganic and Medicinal Chemistry Letters, 1999 , vol. 9, # 9 p. 1335 - 1340

541-47-93,3-二甲基丙烯酸

20364-31-24,4-二甲基-1,2,3,4-四氢喹啉

参考文献

Vertex Pharmaceuticals Incorported
Patent: US2011/98311 A1, 2011 ;

3350-78-53-甲基巴豆酰氯

20364-31-24,4-二甲基-1,2,3,4-四氢喹啉

参考文献

Higuchi, Robert I.; Edwards, James P.; Caferro, Thomas R.; Ringgenberg, Josef D.; Kong, James W.; Hamann, Lawrence G.; Arienti, Kristen L.; Marschke, Keith B.; Davis, Robert L.; Farmer, Luc J.; Jones, Todd K.
Bioorganic and Medicinal Chemistry Letters, 1999 , vol. 9, # 9 p. 1335 - 1340

74497-02-2

20364-31-24,4-二甲基-1,2,3,4-四氢喹啉

参考文献

Higuchi, Robert I.; Edwards, James P.; Caferro, Thomas R.; Ringgenberg, Josef D.; Kong, James W.; Hamann, Lawrence G.; Arienti, Kristen L.; Marschke, Keith B.; Davis, Robert L.; Farmer, Luc J.; Jones, Todd K.
Bioorganic and Medicinal Chemistry Letters, 1999 , vol. 9, # 9 p. 1335 - 1340

74497-02-2+

78-79-5异戊二烯

20364-30-12,2-二甲基-1,2,3,4-四氢喹啉+

20364-31-24,4-二甲基-1,2,3,4-四氢喹啉

参考文献

Clemo; Ghatge
Journal of the Chemical Society, 1955 , p. 4347

7553-56-2碘+

74497-02-2+

78-79-5异戊二烯

20364-30-12,2-二甲基-1,2,3,4-四氢喹啉+

20364-31-24,4-二甲基-1,2,3,4-四氢喹啉

参考文献

Clemo; Ghatge
Journal of the Chemical Society, 1955 , p. 4347

20364-31-24,4-二甲基-1,2,3,4-四氢喹啉

870072-60-9

参考文献

Bristol-Myers Squibb Company
Patent: US2006/293281 A1, 2006 ;
Location in patent: Page/Page column 70 ;
US 20060293281 A1

20364-31-24,4-二甲基-1,2,3,4-四氢喹啉+

577-19-51-溴-2-硝基苯

870072-60-9

参考文献

Qiao, Jennifer X.; Wang, Tammy C.; Ruel, Rejean; Thibeault, Carl; L'Heureux, Alexandre; Schumacher, William A.; Spronk, Steven A.; Hiebert, Sheldon; Bouthillier, Gilles; Lloyd, John; Pi, Zulan; Schnur, Dora M.; Abell, Lynn M.; Hua, Ji; Price, Laura A.; Liu, Eddie; Wu, Qimin; Steinbacher, Thomas E.; Bostwick, Jeffrey S.; Chang, Ming; Zheng, Joanna; Gao, Qi; Ma, Baoqing; McDonnell, Patricia A.; Huang, Christine S.; Rehfuss, Robert; Wexler, Ruth R.; Lam, Patrick Y. S.
Journal of Medicinal Chemistry, 2013 , vol. 56, # 22 p. 9275 - 9295