5-羟基-六氢环戊并[c]吡咯-2(1h)-羧酸叔丁酯合成路线 （共 3 条）
反应条件
sodium tetrahydroborate; ethanol
T=20°C; 4.5 h;
参考文献
XI, Ning; WANG, Tingjin; YI, Lei
Patent: WO2013/138210 A1, 2013 ;
Location in patent: Paragraph 0296 ;
反应条件
1: lithium aluminium tetrahydride / tetrahydrofuran / 21 h / 60 °C
2: dichloromethane / 21.5 h / 0 - 20 °C
3: sodium periodate; ruthenium(IV) oxide / acetonitrile; water; tetrachloromethane / 24 h / 20 °C
4: sodium acetate; acetic anhydride / 3 h / 120 °C
5: sodium tetrahydroborate; ethanol / 4.5 h / 20 °C
View Scheme
参考文献
XI, Ning; WANG, Tingjin; YI, Lei
Patent: WO2013/138210 A1, 2013 ;
反应条件
1: dichloromethane / 21.5 h / 0 - 20 °C
2: sodium periodate; ruthenium(IV) oxide / acetonitrile; water; tetrachloromethane / 24 h / 20 °C
3: sodium acetate; acetic anhydride / 3 h / 120 °C
4: sodium tetrahydroborate; ethanol / 4.5 h / 20 °C
View Scheme
参考文献
XI, Ning; WANG, Tingjin; YI, Lei
Patent: WO2013/138210 A1, 2013 ;
