6-氯-1H-苯并[d]咪唑-2-氨基甲酸甲酯合成路线 (共 2 条)
反应条件
in hydrochloric acid-methanol
反应条件
1: 2-methyl-2-thiopseudourea sulfate; methyl chloroformate With sodium hydroxide T=10 - 15°C; pH=8.0; 2: 4-Chloro-benzene-1,2-diamine With acetic acid T=95°C; pH=5.0; 2 h;
参考文献
Valdez, Juan; Cedillo, Roberto; Hernandez-Campos, Alicia; Yepez, Lilian; Hernandez-Luis, Francisco; Navarrete-Vazquez, Gabriel; Tapia, Amparo; Cortes, Rafael; Hernandez, Manuel; Castillo, Rafael
Bioorganic and medicinal chemistry letters, 2002 , vol. 12, # 16 p. 2221 - 2224