N-(4-羟基苯乙基)-4-羟基苯丙烯酰胺合成路线 （共 6 条）
反应条件
benzotriazol-1-ol; dicyclohexyl-carbodiimide in N,N-dimethyl-formamide T=80°C; Acylation; 12 h;
参考文献
Tamiz, Amir P.; Cai, Sui Xiong; Zhou, Zhang-Lin; Yuen, Po-Wai; Schelkun, Robert M.; Whittemore, Edward R.; Weber, Eckard; Woodward, Richard M.; Keana, John F. W.
Journal of Medicinal Chemistry, 1999 , vol. 42, # 17 p. 3412 - 3420
反应条件
tetrabutylammomium bromide; palladium diacetate; N-ethyl-N,N-diisopropylamine in N,N-dimethyl-formamide T=130 - 140°C; Heck reaction; Microwave irradiationContinuous-flow conditions;
参考文献
Achanta, Srinivas; Liautard, Virginie; Paugh, Robert; Organ, Michael G.
Chemistry - A European Journal, 2010 , vol. 16, # 43 p. 12797 - 12800
反应条件
sodium hydrogencarbonate in water; acetone 24 h;
参考文献
Muehlenbeck, Ute; Kortenbusch, Albertus; Barz, Wolfgang
Phytochemistry, 1996 , vol. 42, # 6 p. 1573 - 1579
反应条件
sodium carbonate in ethanol 2 h; Heating; Yield given;
参考文献
Tseng; Iwakami; Mikajiri; Shibuya; Hanaoka; Ebizuka; Padmawinata; Sankawa
Chemical and Pharmaceutical Bulletin, 1992 , vol. 40, # 2 p. 396 - 400
反应条件
1: Et3N / tetrahydrofuran 2: Et3N / tetrahydrofuran / Ambient temperature 3: 3percent aq. Na2CO3 / ethanol / 2 h / Heating View Scheme
参考文献
Tseng; Iwakami; Mikajiri; Shibuya; Hanaoka; Ebizuka; Padmawinata; Sankawa
Chemical and Pharmaceutical Bulletin, 1992 , vol. 40, # 2 p. 396 - 400
反应条件
1: Et3N / tetrahydrofuran / Ambient temperature 2: 3percent aq. Na2CO3 / ethanol / 2 h / Heating View Scheme
参考文献
Tseng; Iwakami; Mikajiri; Shibuya; Hanaoka; Ebizuka; Padmawinata; Sankawa
Chemical and Pharmaceutical Bulletin, 1992 , vol. 40, # 2 p. 396 - 400
