iodosylbenzene; 1-butylpyridinium tetrafluoroborate; [MnIIIT(N-Me-4-Py)P][PF6]5 T=30°C; 4 h; in open air; Title compound not separated from byproducts.;
1: N,N-dimethyl acetamide With trifluoromethylsulfonic anhydride in anhydrous dichloroethane T=-12°C; 2: 1-bromo-4-ethenylbenzene With 2,4,6-trimethyl-pyridine in anhydrous dichloroethane T=150°C; 3: With water in anhydrous dichloroethane T=80°C; 20 h;
参考文献
PFIZER INC.; ASPNES, Gary, Erik; DOW, Robert, Lee; MUNCHHOF, Michael, John
Patent: WO2010/86820 A1, 2010 ;
Location in patent: Page/Page column 43 ;
WO 2010/086820 A1
1: 1-bromo-4-ethenylbenzene With n-butyllithium in tetrahydrofuran; hexane T=-78°C; 1.5 h; Inert atmosphere; 2: With sulfur in tetrahydrofuran; hexane T=-78 - -10°C; Inert atmosphere; 3: acetic anhydride in tetrahydrofuran; hexane T=-78°C; Inert atmosphere;
参考文献
Lange, Heiko; Capener, Matthew J.; Jones, Alexander X.; Smith, Catherine J.; Nikbin, Nikzad; Baxendale, Ian R.; Ley, Steven V.
Synlett, 2011 , # 6 p. 869 - 873
