1-(4-甲氧基苯基)-2,2-二甲基丙烷-1-酮合成路线 （共 29 条）
反应条件
bismuth(III) chloride
T=100°C; Friedel-Crafts acylation reaction; 3 h;
参考文献
Repichet, Sigrid; Le Roux, Christophe; Roques, Nicolas; Dubac, Jacques
Tetrahedron Letters, 2003 , vol. 44, # 10 p. 2037 - 2040
反应条件
1: With triethyl borane in hexane; toluene
T=90°C; 3 h; Air atmosphere;
2: With water; sodium hydrogencarbonate in hexane; toluene
参考文献
Kim, Joong-Gon; Mishra, Mithilesh Kumar; Jang, Doo Ok
Tetrahedron Letters, 2012 , vol. 53, # 27 p. 3527 - 3529
反应条件
lithium perchlorate; hafnium(IV) trifluoromethanesulfonate in nitromethane
Ambient temperature;
参考文献
Hachiya, Iwao; Moriwaki, Mitsuhiro; Kobayashi, Shu
Bulletin of the Chemical Society of Japan, 1995 , vol. 68, # 7 p. 2053 - 2060
反应条件
C10H16NO5; potassium carbonate; bis-[(trifluoroacetoxy)iodo]benzene in dichloromethane
T=0°C; Resolution of racemate;
参考文献
Hamada, Shohei; Wada, Yoshiyuki; Sasamori, Takahiro; Tokitoh, Norihiro; Furura, Takumi; Kawabata, Takeo
Tetrahedron Letters, 2014 , vol. 55, # 11 p. 1943 - 1945
反应条件
copper(l) iodide; lithium tert-butylate in tetrahydrofuran; pentane
T=-78°C; 0.5 h; Inert atmosphere;
参考文献
Fujihara, Tetsuaki; Semba, Kazuhiko; Terao, Jun; Tsuji, Yasushi
Angewandte Chemie - International Edition, 2010 , vol. 49, # 8 p. 1472 - 1476
反应条件
1: 1-bromo-4-methoxy-benzene With n-butyllithium in tetrahydrofuran; hexane
T=-78°C; 0.5 h;
2: pivalaldehyde in tetrahydrofuran; hexane
T=-78°C; 1 h;
3: With iodine; potassium carbonate in tert-butyl alcohol
5 h; Reflux;
参考文献
Ushijima, Sousuke; Dohi, Souya; Moriyama, Katsuhiko; Togo, Hideo
Tetrahedron, 2012 , vol. 68, # 5 p. 1436 - 1442
反应条件
phosphate buffer; NADPH generating system (NADP+, glucose 6-phosphate, glucose 6-phosphate dehydrogenase, ammonium sulfate buffer); cytochrome P-450 from rat liver microsomes in water
T=36°C; 0.0833333 h;
参考文献
Baciocchi, Enrico; Belvedere, Sandro; Bietti, Massimo; Lanzalunga, Osvaldo
European Journal of Organic Chemistry, 1998 , # 2 p. 299 - 302
反应条件
Titanium(IV) oxide; silver sulphate in acetonitrile
T=20°C; 1 h; Irradiation;
参考文献
Bettoni, Marta; Del Giacco, Tiziana; Rol, Cesare; Sebastiani, Giovanni V.
Journal of Physical Organic Chemistry, 2006 , vol. 19, # 1 p. 18 - 24
反应条件
ozone in acetonitrile
参考文献
Rac, V. Pushkara; Ramamurthy, V.
Tetrahedron, 1985 , vol. 41, # 11 p. 2169 - 2176
反应条件
Titanium(IV) oxide; silver sulphate in acetonitrile
Oxidation; elimination; 2 h; Irradiation;
参考文献
Ranchella, Michele; Rol, Cesare; Sebastiani, Giovanni V.
Journal of the Chemical Society. Perkin Transactions 2, 2000 , # 2 p. 311 - 315
