3-(4-甲氧基苯基)丙醛合成路线 （共 75 条）
反应条件
1: 50.6 percent / LiAlH4 / tetrahydrofuran / 6 h / Heating 2: 94.9 percent / K2CO3 / acetone 3: 51.9 percent / PCC / CH2Cl2 / 1.5 h / 20 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 45, # 12 p. 2358 - 2361
反应条件
1: 96 percent / lithium aluminum hydride / tetrahydrofuran / 4 h / Heating 2: 96 percent / pyridinium chlorochromate / CH2Cl2 / 1 h / 20 °C View Scheme
参考文献
European Journal of Pharmaceutical Sciences, , vol. 23, # 4-5 p. 363 - 369
反应条件
[(dppf)Pt(H2O)2](OTf)2; hydrogen; sodium lauryl sulfate in water T=70°C; P=60006 Torr; 22 h; Autoclave;
参考文献
Gottardo, Marina; Scarso, Alessandro; Paganelli, Stefano; Strukul, Giorgio
Advanced Synthesis and Catalysis, 2010 , vol. 352, # 13 p. 2251 - 2262
反应条件
1: hydrogen / palladium 10 on activated carbon / ethanol / 6 h / 10 - 35 °C 2: diisobutylaluminium hydride / toluene / 1 h / -78 °C View Scheme
反应条件
1: potassium carbonate / N,N-dimethyl-formamide / 4 h / 60 °C 2: diisobutylaluminium hydride / dichloromethane; toluene / -78 °C / |Inert atmosphere View Scheme
参考文献
Organic Letters, , vol. 15, # 23 p. 6058 - 6061
反应条件
1: 94.9 percent / K2CO3 / acetone 2: 51.9 percent / PCC / CH2Cl2 / 1.5 h / 20 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 45, # 12 p. 2358 - 2361
反应条件
1: 1.) aluminium chloride, 2.) sodium dithionite, sodium hydroxide / 1.) 1,1,2,2-tetrachloroethane, room temperature, 16 h; steam-bath, 2 h, 2.) methanol, room temperature, 21 h, reflux, 24 h 2: 88 percent / hydrogen / palladium-carbon / acetic acid / 1.5 h / Ambient temperature 3: 59 percent / lithium aluminium hydride / diethyl ether 4: 62 percent / pyridine 5: 80 percent / lithium bromide / acetone / 24 h / Ambient temperature 6: magnesium (from magnesium chloride and potassium metal, 3-(4-methoxyphenyl)propanal / tetrahydrofuran 7: 74 percent / pyridinium chlorochromate / CH2Cl2 / 4.5 h View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 614 - 622
反应条件
1: 88 percent / hydrogen / palladium-carbon / acetic acid / 1.5 h / Ambient temperature 2: 59 percent / lithium aluminium hydride / diethyl ether 3: 62 percent / pyridine 4: 80 percent / lithium bromide / acetone / 24 h / Ambient temperature 5: magnesium (from magnesium chloride and potassium metal, 3-(4-methoxyphenyl)propanal / tetrahydrofuran 6: 74 percent / pyridinium chlorochromate / CH2Cl2 / 4.5 h View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 614 - 622
反应条件
pyridine-2,6-dicarboxylic acid; Fe(BF4)2*6H2O; iodosylbenzene in chloroform T=59.84°C; 48 h; Molecular sieve; regioselective reaction;
参考文献
Chowdhury, Abhishek Dutta; Ray, Ritwika; Lahiri, Goutam Kumar
Chemical Communications, 2012 , vol. 48, # 44 p. 5497 - 5499
反应条件
C51H41P2Ru(1+)*C32H12BF24(1-) in toluene T=20°C; 4 h;
参考文献
Chemical Science, , vol. 5, # 1 p. 180 - 188
