2,2-二甲基-1-(2-甲基苯基)-1-丙酮合成路线 （共 16 条）
反应条件
1: 1.) LDA / 1.) THF, -78 deg C, 5 min 2: 42 percent / CHCl3 / 7 h / Irradiation View Scheme
参考文献
Kobayashi, Kazuhiro; Konishi, Atsushi; Kanno, Yoshikazu; Suginome, Hiroshi
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1993 , # 1 p. 111 - 116
反应条件
1: 1.) LDA / 1.) THF, -78 deg C, 5 min 2: 1.) lithium 2,2,6,6-tetramethylpiperidine / 1.) THF, -78 deg C 3: 1.) HgO (red), I2 / 1.) benzene, 2.) 8 h, irradiation View Scheme
参考文献
Kobayashi, Kazuhiro; Konishi, Atsushi; Kanno, Yoshikazu; Suginome, Hiroshi
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1993 , # 1 p. 111 - 116
反应条件
ruthenium(II)-carbonyl-tris(triphenylphosphine) dihydride in xylene
1 h; Heating;
参考文献
Kakiuchi, Fumitoshi; Usui, Mayumi; Ueno, Satoshi; Chatani, Naoto; Murai, Shinji
Journal of the American Chemical Society, 2004 , vol. 126, # 9 p. 2706 - 2707
反应条件
1: 1-bromo-2-methyl benzene With diisobutyl-aluminum chloride; diisobutylaluminium hydride; magnesium; lithium chloride in tetrahydrofuran; n-heptane
T=25°C;
2: pivaloyl chloride With CuCN*2LiCl in tetrahydrofuran; n-heptane
T=-10 - 25°C; 3 h;
参考文献
Gao, Hongjun; Knochel, Paul
Synlett, 2009 , # 8 p. 1321 - 1325
反应条件
iodine
0.25 h; Ambient temperatureIrradiation;
参考文献
Gopalakrishnan, Geetha; Anandhi; Narasimhan
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 1996 , vol. 35, # 11 p. 1197 - 1198
反应条件
1: 1.) Mg / 1.) Et2O, reflux, 2.) Et2O, 1 h, 0 deg C
2: 75 percent / PCC/ Celite / CH2Cl2 / 12 h
View Scheme
参考文献
Kobayashi, Kazuhiro; Konishi, Atsushi; Kanno, Yoshikazu; Suginome, Hiroshi
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1993 , # 1 p. 111 - 116
反应条件
1: 1.) Mg / 1.) Et2O, reflux, 2.) Et2O, 1 h, 0 deg C
2: 75 percent / PCC/ Celite / CH2Cl2 / 12 h
View Scheme
参考文献
Kobayashi, Kazuhiro; Konishi, Atsushi; Kanno, Yoshikazu; Suginome, Hiroshi
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1993 , # 1 p. 111 - 116
反应条件
aluminium trichloride
T=0°C;
参考文献
Rothstein; Saville
Journal of the Chemical Society, 1949 , p. 1950,1953
反应条件
in diethyl ether
Heating;
参考文献
Pine,S.H. et al.
Journal of Organic Chemistry, 1971 , vol. 36, p. 984 - 991
参考文献
Ramart-Lucas; Hoch
Bulletin de la Societe Chimique de France, 1952 , p. 220,224
