1,2-二(苯基)丙-1-酮合成路线 （共 138 条）
反应条件
sodium t-butanolate; (SIPr)Pd(allyl)Cl in tetrahydrofuran
T=70°C; 1 h; Product distribution; Further Variations:Catalysts;
参考文献
Viciu, Mihai S.; Germaneau, Romain F.; Nolan, Steven P.
Organic Letters, 2002 , vol. 4, # 23 p. 4053 - 4055
反应条件
1: bromobenzene With sodium t-butanolate; palladium diacetate; tri-tert-butylphosphonium tetraphenylborate in tetrahydrofuran
T=25°C; 0.5 h;
2: 1-phenyl-propan-1-one in tetrahydrofuran
T=25°C; 17 h; Product distribution / selectivity;
参考文献
HOKKO CHEMICAL INDUSTRY CO. LTD.
Patent: EP1688424 A1, 2006 ;
Location in patent: Page/Page column 86 ;
反应条件
tris-(dibenzylideneacetone)dipalladium(0); zinc(II) chloride; tri-cyclo-hexyl-phosphine in tetrahydrofuran
T=28°C; Fukuyama Coupling; 12 h; Schlenk techniqueInert atmosphere;
参考文献
Cherney, Alan H.; Reisman, Sarah E.
Tetrahedron, 2014 , vol. 70, # 20 p. 3259 - 3265
反应条件
tris-(dibenzylideneacetone)dipalladium(0); zinc(II) chloride; tri-cyclo-hexyl-phosphine in tetrahydrofuran
T=28°C; Fukuyama Coupling; 12 h; Schlenk techniqueInert atmosphere;
参考文献
Cherney, Alan H.; Reisman, Sarah E.
Tetrahedron, 2014 , vol. 70, # 20 p. 3259 - 3265
反应条件
1: α-phenylacetophenone With potassium tert-butylate in tetrahydrofuran
T=0°C; 0.333333 h;
2: methyl iodide in tetrahydrofuran
T=0°C; 2 h;
参考文献
Li, Zhou; Gevorgyan, Vladimir
Angewandte Chemie - International Edition, 2011 , vol. 50, # 12 p. 2808 - 2810
反应条件
sodium t-butanolate; (SIPr)Pd(allyl)Cl in tetrahydrofuran
T=60°C; 1.5 h;
参考文献
Viciu, Mihai S.; Germaneau, Romain F.; Nolan, Steven P.
Organic Letters, 2002 , vol. 4, # 23 p. 4053 - 4055
反应条件
potassium phosphate; Ni(PPh3)4 in toluene
T=60°C; 16 h;
参考文献
Liu, Chao; He, Chuan; Shi, Wei; Chen, Mao; Lei, Aiwen
Organic Letters, 2007 , vol. 9, # 26 p. 5601 - 5604
反应条件
1: phenyl-magnesium chloride With AlCl3, aluminium chloride in tetrahydrofuran
2: 1-phenyl-propan-1-one With dihydro-isoxazole in tetrahydrofuran; dichloromethane
T=0 - 20°C;
参考文献
Miyoshi, Tetsuya; Sato, Shohei; Tanaka, Hiroya; Hasegawa, Chihiro; Ueda, Masafumi; Miyata, Okiko
Tetrahedron Letters, 2012 , vol. 53, # 32 p. 4188 - 4191
反应条件
1,1'-bis-(di-tert-butylphosphino)ferrocene; bis(dibenzylideneacetone)-palladium(0); sodium t-butanolate in tetrahydrofuran
T=25°C; 2 h;
参考文献
Kawatsura, Motoi; Hartwig, John F.
Journal of the American Chemical Society, 1999 , vol. 121, # 7 p. 1473 - 1478
反应条件
gallium(III) chloride; 2-methyl cyclohexane
T=20°C; 1 h;
参考文献
Oshita, Masayuki; Okazaki, Takao; Ohe, Kouichi; Chatani, Naoto
Organic Letters, 2005 , vol. 7, # 2 p. 331 - 334
