1,2-二(苯基)丙-1-酮合成路线 （共 138 条）
参考文献
Yates,P. et al.
Canadian Journal of Chemistry, 1971 , vol. 49, p. 1691 - 1706
反应条件
sodium periodate in ethanol; water
6 h; Yield given;
参考文献
Chantrapromma, Kan; Ollis, W. David; Sutherland, Ian O.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , # 5 p. 1049 - 1062
反应条件
hydrogen; ozone; Lindlar's catalyst
1.) AcOEt, -5 deg C; Yield given. Multistep reaction;
参考文献
Chantrapromma, Kan; Ollis, W. David; Sutherland, Ian O.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , # 5 p. 1049 - 1062
反应条件
1: 81 percent / NaH / tetrahydrofuran / 1.) 0 deg C, 45 min, 2.) 2 h
2: 83 percent / Me2PhSiLi / tetrahydrofuran / 1.) -78 deg C, 1.5 h, 2.) 0 deg C, 5 h
View Scheme
参考文献
Fleming, Ian; Roberts, Richard S.; Smith, Stephen C.
Journal of the Chemical Society - Perkin Transactions 1, 1998 , # 7 p. 1215 - 1228
反应条件
1: 75 percent / diethyl ether; tetrahydrofuran / 1.5 h / -78 °C
2: 81 percent / NaH / tetrahydrofuran / 1.) 0 deg C, 45 min, 2.) 2 h
3: 83 percent / Me2PhSiLi / tetrahydrofuran / 1.) -78 deg C, 1.5 h, 2.) 0 deg C, 5 h
View Scheme
参考文献
Fleming, Ian; Roberts, Richard S.; Smith, Stephen C.
Journal of the Chemical Society - Perkin Transactions 1, 1998 , # 7 p. 1215 - 1228
反应条件
1: 2.) SOCl2, pyridine, 3.) HCl
2: 1.) O3, 2.) H2 / 2.) Pd-CaCO3 / 1.) AcOEt, -5 deg C
View Scheme
参考文献
Chantrapromma, Kan; Ollis, W. David; Sutherland, Ian O.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , # 5 p. 1049 - 1062
反应条件
1: 710 mg / NaBH4 / ethanol / 12 h / Ambient temperature
2: NaIO4 / ethanol; H2O / 6 h
View Scheme
参考文献
Chantrapromma, Kan; Ollis, W. David; Sutherland, Ian O.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , # 5 p. 1049 - 1062
反应条件
1: 72 percent / Zn dust, AcOH / 0.25 h / 80 - 90 °C
2: 2.) SOCl2, pyridine, 3.) HCl
3: 1.) O3, 2.) H2 / 2.) Pd-CaCO3 / 1.) AcOEt, -5 deg C
View Scheme
参考文献
Chantrapromma, Kan; Ollis, W. David; Sutherland, Ian O.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , # 5 p. 1049 - 1062
反应条件
1: 1.) Mg / 1.) Et2O, 2.) Et2O, 6 h
2: chromium trioxide-pyridine / CH2Cl2 / 0.25 h / Ambient temperature
View Scheme
参考文献
Alvarez-Ibarra, Carlos; Arjona, Odon; Perez-Ossorio, Rafael; Perez-Rubalcaba, Alfredo; Quiroga, Maria L.; Santesmases, Maria J.
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1983 , # 11 p. 1645 - 1648
反应条件
1: Py
2: Zn / 165 °C
View Scheme
参考文献
Ghera,E.
Journal of Organic Chemistry, 1970 , vol. 35, p. 660 - 666
