1.1: pyridine / dichloromethane / 1 h / -15 °C / |Inert atmosphere 2.1: sodium azide / N,N-dimethyl-formamide / 2 h / 20 °C 3.1: triphenylphosphine / tetrahydrofuran / 4 h / 20 °C 3.2: 4 h / 20 °C 4.1: pyridine / 2 h / 0 - 20 °C 5.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 4 h / 20 °C / |Inert atmosphere 6.1: dimethyl sulfoxide; oxalyl dichloride / dichloromethane / 1 h / -78 °C / |Inert atmosphere 6.2: 0.75 h / -78 - 20 °C / |Inert atmosphere 7.1: titanium tetrachloride / dichloromethane / 0.25 h / 0 °C / |Inert atmosphere 7.2: 2 h / 0 °C / |Inert atmosphere 8.1: 10 Pd/C; hydrogen / ethanol / 96 h / 20 °C 9.1: sodium hydride / tetrahydrofuran / 1 h / 0 °C / |Inert atmosphere 10.1: triethylamine / dichloromethane / 0.75 h / 0 °C 11.1: sodium azide / ethanol; water / 8 h / |Reflux 12.1: triphenylphosphine / tetrahydrofuran / 4 h / 20 °C 12.2: Staudinger Azide Reduction / 24 h / 20 °C 13.1: phosphoric acid / ethanol / 0 - 50 °C View Scheme

1.1: triphenylphosphine / tetrahydrofuran / 4 h / 20 °C 1.2: 4 h / 20 °C 2.1: pyridine / 2 h / 0 - 20 °C 3.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 4 h / 20 °C / |Inert atmosphere 4.1: dimethyl sulfoxide; oxalyl dichloride / dichloromethane / 1 h / -78 °C / |Inert atmosphere 4.2: 0.75 h / -78 - 20 °C / |Inert atmosphere 5.1: titanium tetrachloride / dichloromethane / 0.25 h / 0 °C / |Inert atmosphere 5.2: 2 h / 0 °C / |Inert atmosphere 6.1: 10 Pd/C; hydrogen / ethanol / 96 h / 20 °C 7.1: sodium hydride / tetrahydrofuran / 1 h / 0 °C / |Inert atmosphere 8.1: triethylamine / dichloromethane / 0.75 h / 0 °C 9.1: sodium azide / ethanol; water / 8 h / |Reflux 10.1: triphenylphosphine / tetrahydrofuran / 4 h / 20 °C 10.2: Staudinger Azide Reduction / 24 h / 20 °C 11.1: phosphoric acid / ethanol / 0 - 50 °C View Scheme

1.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 4 h / 20 °C / |Inert atmosphere 2.1: dimethyl sulfoxide; oxalyl dichloride / dichloromethane / 1 h / -78 °C / |Inert atmosphere 2.2: 0.75 h / -78 - 20 °C / |Inert atmosphere 3.1: titanium tetrachloride / dichloromethane / 0.25 h / 0 °C / |Inert atmosphere 3.2: 2 h / 0 °C / |Inert atmosphere 4.1: 10 Pd/C; hydrogen / ethanol / 96 h / 20 °C 5.1: sodium hydride / tetrahydrofuran / 1 h / 0 °C / |Inert atmosphere 6.1: triethylamine / dichloromethane / 0.75 h / 0 °C 7.1: sodium azide / ethanol; water / 8 h / |Reflux 8.1: triphenylphosphine / tetrahydrofuran / 4 h / 20 °C 8.2: Staudinger Azide Reduction / 24 h / 20 °C 9.1: phosphoric acid / ethanol / 0 - 50 °C View Scheme

1.1: dimethyl sulfoxide; oxalyl dichloride / dichloromethane / 1 h / -78 °C / |Inert atmosphere 1.2: 0.75 h / -78 - 20 °C / |Inert atmosphere 2.1: titanium tetrachloride / dichloromethane / 0.25 h / 0 °C / |Inert atmosphere 2.2: 2 h / 0 °C / |Inert atmosphere 3.1: 10 Pd/C; hydrogen / ethanol / 96 h / 20 °C 4.1: sodium hydride / tetrahydrofuran / 1 h / 0 °C / |Inert atmosphere 5.1: triethylamine / dichloromethane / 0.75 h / 0 °C 6.1: sodium azide / ethanol; water / 8 h / |Reflux 7.1: triphenylphosphine / tetrahydrofuran / 4 h / 20 °C 7.2: Staudinger Azide Reduction / 24 h / 20 °C 8.1: phosphoric acid / ethanol / 0 - 50 °C View Scheme

1.1: titanium tetrachloride / dichloromethane / 0.25 h / 0 °C / |Inert atmosphere 1.2: 2 h / 0 °C / |Inert atmosphere 2.1: 10 Pd/C; hydrogen / ethanol / 96 h / 20 °C 3.1: sodium hydride / tetrahydrofuran / 1 h / 0 °C / |Inert atmosphere 4.1: triethylamine / dichloromethane / 0.75 h / 0 °C 5.1: sodium azide / ethanol; water / 8 h / |Reflux 6.1: triphenylphosphine / tetrahydrofuran / 4 h / 20 °C 6.2: Staudinger Azide Reduction / 24 h / 20 °C 7.1: phosphoric acid / ethanol / 0 - 50 °C View Scheme

1.1: sodium hydride / tetrahydrofuran / 1 h / 0 °C / |Inert atmosphere 2.1: triethylamine / dichloromethane / 0.75 h / 0 °C 3.1: sodium azide / ethanol; water / 8 h / |Reflux 4.1: triphenylphosphine / tetrahydrofuran / 4 h / 20 °C 4.2: Staudinger Azide Reduction / 24 h / 20 °C 5.1: phosphoric acid / ethanol / 0 - 50 °C View Scheme

1: sodium acetate / water / 4 h / 110 - 116 °C 2: hydrogenchloride / water; ethanol / 13 - 25 °C 3: trifluoroacetic acid / 1.5 h / 50 °C 4: N,N'-dimethyl-barbituric acid; triphenylphosphine; palladium diacetate / ethanol / 2 h / 35 °C / |Sealed tube; |Inert atmosphere 5: phosphoric acid / ethanol / 50 °C View Scheme

1: hydrogenchloride / water; ethanol / 13 - 25 °C 2: trifluoroacetic acid / 1.5 h / 50 °C 3: N,N'-dimethyl-barbituric acid; triphenylphosphine; palladium diacetate / ethanol / 2 h / 35 °C / |Sealed tube; |Inert atmosphere 4: phosphoric acid / ethanol / 50 °C View Scheme

1.1: Magnesium chloride / toluene / 6 h / 25 °C 1.2: 20 h / 20 - 50 °C 2.1: methanesulfonyl chloride / toluene / 1.5 h / 5 - 10 °C 2.2: 6 h / 5 - 70 °C 3.1: benzenesulfonic Acid / 5.5 h / 120 °C 4.1: sodium acetate / water / 4 h / 110 - 116 °C 5.1: hydrogenchloride / water; ethanol / 13 - 25 °C 6.1: trifluoroacetic acid / 1.5 h / 50 °C 7.1: N,N'-dimethyl-barbituric acid; triphenylphosphine; palladium diacetate / ethanol / 2 h / 35 °C / |Sealed tube; |Inert atmosphere 8.1: phosphoric acid / ethanol / 50 °C View Scheme

1.1: methanesulfonyl chloride / toluene / 1.5 h / 5 - 10 °C 1.2: 6 h / 5 - 70 °C 2.1: benzenesulfonic Acid / 5.5 h / 120 °C 3.1: sodium acetate / water / 4 h / 110 - 116 °C 4.1: hydrogenchloride / water; ethanol / 13 - 25 °C 5.1: trifluoroacetic acid / 1.5 h / 50 °C 6.1: N,N'-dimethyl-barbituric acid; triphenylphosphine; palladium diacetate / ethanol / 2 h / 35 °C / |Sealed tube; |Inert atmosphere 7.1: phosphoric acid / ethanol / 50 °C View Scheme