1-碘-1H,1H,2H,2H-全氟辛烷合成路线 （共 102 条）
反应条件
magnesium; (η4-C8H12)CuCl 1.) Et2O, 2.) Et2O, 0 deg C to r.t.; Multistep reaction;
参考文献
Kainz; Koch; Baumann; Leitner
Angewandte Chemie - International Edition in English, 1997 , vol. 36, # 15 p. 1628 - 1630
反应条件
[CuCl(cod)]; magnesium 1.) Et2O, r.t., overnight, 2.) Et2O, THF, -20 deg C to r.t.; r.t., 4 h; Yield given. Multistep reaction;
参考文献
Kainz, Sabine; Luo, Zhiyong; Curran, Dennis P.; Leitner, Walter
Synthesis, 1998 , # 10 p. 1425 - 1427
反应条件
1: sodium azide; Aliquot 336 / H2O / Heating 2: H2 / Pd/C / diethyl ether / 2585.74 Torr 3: NEt3 / CH2Cl2 4: lithium aluminum hydride / tetrahydrofuran View Scheme
参考文献
Parks, Bevin W.; Gilbertson, Robert D.; Domaille, Dylan W.; Hutchison, James E.
Journal of Organic Chemistry, 2006 , vol. 71, # 26 p. 9622 - 9627
反应条件
acetic acid in ethanol 4 h; Heating / reflux;
参考文献
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE(C.N.R.S.)
Patent: US2008/15255 A1, 2008 ;
Location in patent: Page/Page column 7-8 ;
反应条件
in dimethyl sulfoxide; tert-butyl alcohol T=90°C;
参考文献
Rondestvedt,C.S.; Thayer,G.L.
Journal of Organic Chemistry, 1977 , vol. 42, p. 2680 - 2683
反应条件
(10H)-phenothiazine in tert-butyl alcohol T=160°C; 9 h;
参考文献
Asahi Glass Company, Limited
Patent: EP1486482 A1, 2004 ;
Location in patent: Page 5; 6 ;
反应条件
sodium hydroxide in ethanol T=30°C; 1 h;
参考文献
Brace, Neal O.; Marshall, Lawrence W.; Pinson, Carol J.; Wingerden, Gail van
Journal of Organic Chemistry, 1984 , vol. 49, # 13 p. 2361 - 2368
→
647-42-73,3,4,4,5,5,6,6,7,7,8,8,8-十三氟-1-辛醇+
反应条件
(10H)-phenothiazine in tert-butyl alcohol T=130 - 170°C; 6 - 9 h;
参考文献
Asahi Glass Company, Limited
Patent: EP1486482 A1, 2004 ;
Location in patent: Page 5; 6 ;
反应条件
T=90°C; 24 h; Schlenk technique;
参考文献
Alhanash, Hana B.; Brisdon, Alan K.
Journal of Fluorine Chemistry, 2013 , vol. 156, p. 152 - 157
反应条件
1: malonic acid dimethyl ester With sodium hydride in tetrahydrofuran T=20°C; 0.333333 h; 2: 3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluoro-1-iodooctane in tetrahydrofuran 18 h; Heating;
参考文献
Trabelsi; Szoenyi; Geribaldi
Journal of Fluorine Chemistry, 2001 , vol. 107, # 1 p. 177 - 181
