2-甲基-2-对甲苯丙酸合成路线 （共 10 条）
反应条件
potassium hydroxide in ethylene glycol Heating;
参考文献
Journal of the American Chemical Society, , vol. 90, p. 2082 - 2096
反应条件
1: With n-butyllithium; diisopropylamine in tetrahydrofuran; hexane T=-20°C; 2 h; 2: (4-methylphenyl)acetic acid in tetrahydrofuran; hexane T=-5°C; 2 h; 3: methyl iodide in tetrahydrofuran; hexane T=-5 - 20°C; 15 h;
参考文献
WO2006/27211 A1, ;
Page/Page column 60-61 ;
WO 2006/027211 A1
反应条件
1: liquid ammonia; sodium amide / -35 °C / Behandeln des Reaktionsgemisches mit Methyljodid 2: ethanolic KOH-solution 3: aq. NaOH solution View Scheme
参考文献
Journal of the Chemical Society, , p. 42,46
参考文献
Journal of the Chemical Society, , p. 42,46
反应条件
1: boron fluoride / 50 °C 2: aqueous hydrochloric acid View Scheme
参考文献
Journal of the Chemical Society, , p. 42,46
反应条件
sodium hydroxide; ethanol; silver nitrate
参考文献
Acta Chemica Scandinavica (1947-1973), , vol. 3, p. 279,294
参考文献
Journal of the Chemical Society, , p. 42,46
参考文献
Helvetica Chimica Acta, , vol. 54, p. 868 - 897
参考文献
Journal of Organic Chemistry, , vol. 29, p. 2753
Bulletin de la Societe Chimique de France, , p. 820,822
参考文献
Bulletin de la Societe Chimique de France, , vol. <4> 49, p. 1738,1746
