(4-(三氟甲基)噻唑-2-基)甲醇合成路线 （共 2 条）
反应条件
1: in ethanol 18 h; Heating / reflux; 2: With methanol; 1,8-diazabicyclo[5.4.0]undec-7-ene in ethanol T=20°C; 48 h;
参考文献
MERCK SHARP and DOHME LIMITED; HOLLINGWORTH, Gregory, John; JONES, A., Brian; SPAREY, Timothy, Jason
Patent: WO2005/49613 A1, 2005 ;
Location in patent: Page/Page column 52 ;
WO 2005/049613 A1
反应条件
1: With Dess-Martin periodane in dichloromethane T=0 - 20°C; 3 h; 2: With sodium hydrogencarbonate in dichloromethane 0.166667 h;
参考文献
COMENTIS, INC.; ASTELLAS PHARMA INC.; BILCER, Geoffrey, M.; DEVASAMUDRAM, Thippeswamy; LILLY, John, C.; ANKALA, Sudha, V.; MOSKALEV, Nikolai, V.; LIU, Chunfeng; INOUE, Makoto; KAWAKAMI, Shimpei; MUNAKATA, Ryosuke; HAMAJIMA, Toshihiro
Patent: WO2012/54510 A1, 2012 ;
Location in patent: Page/Page column 91 ;
WO 2012/054510 A1
