2-(4-羟苯基)-2H-异喹啉-1-酮合成路线 （共 3 条）
反应条件
pyridine hydrochloride
T=190°C; 2 h;
参考文献
RVX Therapeutics Inc.; McLure, Kevin G.; Young, Peter Ronald
Patent: US2013/281397 A1, 2013 ;
Location in patent: Paragraph 0429; 0430 ;
反应条件
1.1: pyridine hydrochloride; n-butyllithium / tetrahydrofuran; hexane / 1 h / 0 - 20 °C / |Inert atmosphere
1.2: -50 - 20 °C
2.1: pyridine hydrochloride / 2 h / 190 °C
View Scheme
参考文献
RVX Therapeutics Inc.; McLure, Kevin G.; Young, Peter Ronald
Patent: US2013/281397 A1, 2013 ;
反应条件
1.1: pyridine hydrochloride; n-butyllithium / tetrahydrofuran; hexane / 1 h / 0 - 20 °C / |Inert atmosphere
1.2: -50 - 20 °C
2.1: pyridine hydrochloride / 2 h / 190 °C
View Scheme
参考文献
RVX Therapeutics Inc.; McLure, Kevin G.; Young, Peter Ronald
Patent: US2013/281397 A1, 2013 ;
