N-甲基-2,4-二硝基苯胺合成路线 （共 102 条）
反应条件
1.1: sodium sulfide; sodium hydrogencarbonate / water; methanol / 25 - 80 °C 2.1: 35 - 40 °C 2.2: 80 - 85 °C 2.3: 25 - 30 °C 3.1: hydrogen / Raney nickel / methanol / 25 - 30 °C / 4654.46 - 5171.62 Torr 4.1: N-ethyl-N,N-diisopropylamine / water / 25 - 95 °C 5.1: thionyl chloride / dichloromethane / 25 - 60 °C 5.2: 55 - 60 °C View Scheme
反应条件
formic acid; triethylamine in acetonitrile 3 h; Heating;
参考文献
Piersanti, Giovanni; Giorgi, Luca; Bartoccini, Francesca; Tarzia, Giorgio; Minetti, Patrizia; Gallo, Grazia; Giorgi, Fabrizio; Castorina, Massimo; Ghirardi, Orlando; Carminati, Paolo
Organic and Biomolecular Chemistry, 2007 , vol. 5, # 16 p. 2567 - 2571
反应条件
sodium hydroxide; anhydrous sodium hydrogen carbonate in methanol; water
参考文献
Ciba-Geigy Corporation
Patent: US4138568 A1, 1979 ;
参考文献
Kehrmann; Messinger
Journal fuer Praktische Chemie (Leipzig), 1892 , vol. <2> 46, p. 574
Chemische Berichte, 1893 , vol. 26, p. 2374
Full Text Show Details
Kehrmann
Chemische Berichte, 1895 , vol. 28, p. 1716
反应条件
dinitrogen pentaoxide
参考文献
Daszkiewicz; Kyziol; Predo; Zaleski
Journal of Molecular Structure, 2000 , vol. 553, # 1-3 p. 9 - 18
参考文献
van Romburgh
Recueil des Travaux Chimiques des Pays-Bas, 1889 , vol. 8, p. 249
反应条件
1: water; nitric acid 2: H2SO4 View Scheme
参考文献
Journal of the Chemical Society, , p. 1556,1561
反应条件
bromine; acetic acid
参考文献
Chemische Berichte, , vol. 15, p. 1234
反应条件
1: alcohol; aqueous sodium hydrosulfide
2: alcohol; concentrated hydrochloric acid
View Scheme
参考文献
Brand; Wild
Chemische Berichte, 1923 , vol. 56, p. 110
反应条件
1: triethylamine; formic acid / palladium on activated charcoal / acetonitrile / 4.5 h / -15 - 80 °C
2: N,N-dimethyl-formamide / 2 h / 20 °C
View Scheme
参考文献
AURIGENE DISCOVERY TECHNOLOGIES LIMITED; SENGUPTA, Saumitra; RAJAGOPALAN, Srinivasan; BELAVAGI, Ningaraddi; RAMACHANDRA, Muralidhara
Patent: WO2012/59932 A1, 2012 ;
WO 2012/059932 A1
