(R)-(+)-α-甲氧基-α-(三氟甲基)苯乙酸合成路线 （共 31 条）
反应条件
in dichloromethane reaction at -78°C for 5 min;; chromy.; elem. anal.;
参考文献
Dalton, Dennis M.; Gladysz, J. A.
Journal of Organometallic Chemistry, 1989 , vol. 370, p. C17 - C28
反应条件
oxalyl dichloride; N,N-dimethyl-formamide in hexane 1 h; Ambient temperature;
参考文献
Boyd, Derek R.; Dorrity, Michael R. J.; Hamilton, Lynne; Malone, John F.; Smith, Allison
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1994 , # 19 p. 2711 - 2714
反应条件
1: With (1S,2R)-1-aminoindan-2-ol in ethanol; ethyl acetate T=30°C; Addition; 12 h; 2: With hydrogenchloride Hydrolysis; Further stages.;
参考文献
Kinbara, Kazushi; Kobayashi, Yuka; Saigo, Kazuhiko
Journal of the Chemical Society. Perkin Transactions 2, 2000 , # 1 p. 111 - 119
参考文献
Tetrahedron Letters, , vol. 30, # 14 p. 1749 - 1752
反应条件
in dichloromethane reaction at -78°C for 5 min;; chromy.; elem. anal.;
参考文献
Dalton, Dennis M.; Gladysz, J. A.
Journal of Organometallic Chemistry, 1989 , vol. 370, p. C17 - C28
反应条件
1: With (1S,2R)-1-aminoindan-2-ol in ethanol; ethyl acetate T=30°C; Addition; 12 h; 2: With hydrogenchloride Hydrolysis; Further stages.;
参考文献
Kinbara, Kazushi; Kobayashi, Yuka; Saigo, Kazuhiko
Journal of the Chemical Society. Perkin Transactions 2, 2000 , # 1 p. 111 - 119
反应条件
1: With (1S,2R)-1-aminoindan-2-ol in ethanol; ethyl acetate T=30°C; Addition; 12 h; 2: With hydrogenchloride Hydrolysis; Further stages.;
参考文献
Kinbara, Kazushi; Kobayashi, Yuka; Saigo, Kazuhiko
Journal of the Chemical Society. Perkin Transactions 2, 2000 , # 1 p. 111 - 119
反应条件
oxalyl dichloride; N,N-dimethyl-formamide in hexane 1 h; Ambient temperature;
参考文献
Boyd, Derek R.; Dorrity, Michael R. J.; Hamilton, Lynne; Malone, John F.; Smith, Allison
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1994 , # 19 p. 2711 - 2714
反应条件
1: With (1S,2R)-1-aminoindan-2-ol in ethanol; ethyl acetate T=30°C; Addition; 12 h; 2: With hydrogenchloride Hydrolysis; Further stages.;
参考文献
Kinbara, Kazushi; Kobayashi, Yuka; Saigo, Kazuhiko
Journal of the Chemical Society. Perkin Transactions 2, 2000 , # 1 p. 111 - 119
反应条件
in dichloromethane reaction at -78°C for 5 min;; chromy.; elem. anal.;
参考文献
Dalton, Dennis M.; Gladysz, J. A.
Journal of Organometallic Chemistry, 1989 , vol. 370, p. C17 - C28
