7-二甲氧基甲基-1,2,3,4-四氢-[1,8]萘啶合成路线 （共 5 条）
反应条件
hydrogen; platinum(IV) oxide in ethanol T=20°C; P=760 Torr; 18 h;
参考文献
Yasuda, Nobuyoshi; Hsiao; Jensen, Mark S; Rivera, Nelo R; Yang, Chunhua; Wells, Kenneth M; Yau, James; Palucki, Michael; Tan, Lushi; Dormer, Peter G; Volante, Ralph P; Hughes, David L; Reider, Paul J
The Journal of organic chemistry, 2004 , vol. 69, # 6 p. 1959 - 1966
反应条件
1: 95 percent / NaOH / ethanol; H2O / 1 h / 20 °C 2: 92 percent / H2 / PtO2 / ethanol / 18 h / 20 °C / 760 Torr View Scheme
参考文献
The Journal of organic chemistry, , vol. 69, # 6 p. 1959 - 1966
反应条件
1: trifluoroacetic acid / 1.5 h / 20 °C / Inert atmosphere 2: hydroxylamine hydrochloride; sodium acetate / water; methanol / 2 h / 60 °C 3: trifluoroacetic acid; zinc / 0.33 h View Scheme
参考文献
Flores, Christopher M.; Wade, Paul R.
Patent: US2011/319400 A1, 2011 ;
反应条件
1: aq. HCl / 2.5 h / 85 °C 2: aq. NaOH / tetrahydrofuran / 20 °C 3: 89 percent / H2; aq. NH4OH / Raney Ni / 16 h / 50 °C / 2068.59 Torr View Scheme
参考文献
Yasuda, Nobuyoshi; Hsiao; Jensen, Mark S; Rivera, Nelo R; Yang, Chunhua; Wells, Kenneth M; Yau, James; Palucki, Michael; Tan, Lushi; Dormer, Peter G; Volante, Ralph P; Hughes, David L; Reider, Paul J
The Journal of organic chemistry, 2004 , vol. 69, # 6 p. 1959 - 1966
反应条件
hydrogenchloride T=85°C; 2.5 h;
参考文献
Payne, Linda S.; Tran, Lekhanh O.; Zhuang, Linghang H.; Young, Steven D.; Egbertson, Melissa S.; Wai, John S.; Embrey, Mark W.; Fisher, Thorsten E.; Guare, James P.; Langford, H. Marie; Melamed, Jeffrey Y.; Clark, David L.
Patent: US2003/229079 A1, 2003 ;
Location in patent: Page 36 ;
