NaY faujasite T=90°C; 26 h;

HRu(1,3-bis(6'-methyl-2'-pyridylimino)isoindoline)(PPh3)2 in toluene T=110°C; 24 h; Inert atmosphereGlovebox; chemoselective reaction;

potassium carbonate in dichloromethane Ambient temperature;

1: 1-amino-2-(2-methoxyphenyl)ethane; 4-formyl-3,5-dimethoxyphenoxy-Merrifield resin With sodium tris(acetoxy)borohydride in acetic acid; N,N-dimethyl-formamide T=20°C; Solid phase reaction; reductive amination; 69 h; 2: chloroacetic acid With benzotriazol-1-ol; dicyclohexyl-carbodiimide in N,N-dimethyl-formamide T=20°C; Solid phase reaction; acylation; 15 h; 3: With dimethylsulfide; water; trifluoroacetic acid in dichloromethane T=20°C; Solid phase reaction; cleavage of amide; 15 h;

1: 100 percent / Et3N / tetrahydrofuran / 24 h / 20 °C 2: 22 percent / polyphosphoric acid / 0.17 h / 145 °C View Scheme

boron tribromide in 4-(dicyanomethylene)-2-methyl-6-(4-dimethylaminostyryl)-4H-pyran

暂无反应条件数据

potassium carbonate in dichloromethane T=0°C;

NaY faujasite T=90°C; 26 h;

1: 12.5 h / 0 °C / |Reflux 2: triethylamine; trichlorophosphate / dichloromethane / 3 h / -10 °C / |Inert atmosphere View Scheme