1: 94 percent / LDA / tetrahydrofuran; hexane / 0.25 h / -78 °C 2: 98 percent / H2 / Pd/C / ethyl acetate / 1 h / 20 °C 3: 95 percent / EDC; HOBT / CH2Cl2 / 17 h / 0 - 20 °C 4: TBAF / tetrahydrofuran / 0.33 h / 20 °C 5: aq. cerium ammonium nitrate / acetonitrile / 0.08 h / 20 °C View Scheme

1.1: LDA / tetrahydrofuran / 1 h / -78 °C 1.2: 90 percent / tetrahydrofuran / 0.25 h / -78 °C 2.1: H2 / Pd/C / ethyl acetate / 20 °C 3.1: aq. (NH4)2Ce(NO3)6 / acetonitrile / 16 h / 0 °C View Scheme