1,2,3,4-四氢环戊[b]吲哚合成路线 （共 42 条）
反应条件
1.1: lithium diisopropyl amide / tetrahydrofuran / -78 °C / Inert atmosphere 1.2: -78 - 20 °C / Inert atmosphere 2.1: iron; acetic acid / ethanol / 80 °C / Inert atmosphere 3.1: trifluoromethanesulfonyl azide; copper(II) sulfate; triethylamine / methanol; dichloromethane; water / 20 °C / Inert atmosphere 4.1: dirhodium(II) tetraoctanoate / 1,2-dichloro-ethane / 16 h / 70 °C / Inert atmosphere; Molecular sieve View Scheme
参考文献
Angewandte Chemie - International Edition, , vol. 50, # 7 p. 1702 - 1706
反应条件
1: C24H29ClIrN6O2(1+)*C32H12BF24(1-) / deuterated toluene / 0.1 h / 100 °C / |Inert atmosphere 2: C24H29ClIrN6O2(1+)*C32H12BF24(1-); potassium tert-butylate / deuterated toluene / 21 h / 110 °C / |Inert atmosphere View Scheme
参考文献
Organometallics, , vol. 31, # 21 p. 7500 - 7510
反应条件
1: sodium hydride / N,N-dimethyl-formamide 2: diisobutylaluminium hydride / toluene / 20 °C / |Inert atmosphere 3: sodium hydride / N,N-dimethyl-formamide / 3 h / 0 - 20 °C / |Inert atmosphere 4: palladium 10 on activated carbon; hydrogen / methanol / 3 h / 20 °C / |Inert atmosphere 5: 1,1-dimethylnitroethane; trimethylsilylazide / acetonitrile / 2 h / 20 °C / |Inert atmosphere; |Cooling 6: FeBr2 / toluene / 16 h / 140 °C / |Schlenk technique; |Inert atmosphere View Scheme
参考文献
Journal of the American Chemical Society, , vol. 135, # 2 p. 620 - 623
反应条件
1: diisobutylaluminium hydride / toluene / 20 °C / |Inert atmosphere 2: sodium hydride / N,N-dimethyl-formamide / 3 h / 0 - 20 °C / |Inert atmosphere 3: palladium 10 on activated carbon; hydrogen / methanol / 3 h / 20 °C / |Inert atmosphere 4: 1,1-dimethylnitroethane; trimethylsilylazide / acetonitrile / 2 h / 20 °C / |Inert atmosphere; |Cooling 5: FeBr2 / toluene / 16 h / 140 °C / |Schlenk technique; |Inert atmosphere View Scheme
参考文献
Journal of the American Chemical Society, , vol. 135, # 2 p. 620 - 623
反应条件
1: sodium hydride / N,N-dimethyl-formamide / 3 h / 0 - 20 °C / |Inert atmosphere 2: palladium 10 on activated carbon; hydrogen / methanol / 3 h / 20 °C / |Inert atmosphere 3: 1,1-dimethylnitroethane; trimethylsilylazide / acetonitrile / 2 h / 20 °C / |Inert atmosphere; |Cooling 4: FeBr2 / toluene / 16 h / 140 °C / |Schlenk technique; |Inert atmosphere View Scheme
参考文献
Journal of the American Chemical Society, , vol. 135, # 2 p. 620 - 623
反应条件
1: palladium 10 on activated carbon; hydrogen / methanol / 3 h / 20 °C / |Inert atmosphere 2: 1,1-dimethylnitroethane; trimethylsilylazide / acetonitrile / 2 h / 20 °C / |Inert atmosphere; |Cooling 3: FeBr2 / toluene / 16 h / 140 °C / |Schlenk technique; |Inert atmosphere View Scheme
参考文献
Journal of the American Chemical Society, , vol. 135, # 2 p. 620 - 623
反应条件
in 2-ethoxy-ethanol Bischler reaction; 0.166667 h; microwave irradiation;
参考文献
Chen, Jing; Hu, Yongzhou
Synthetic Communications, 2006 , vol. 36, # 11 p. 1485 - 1494
反应条件
in toluene 16 h; Heating;
参考文献
Synthesis, , # 11 p. 1635 - 1638
反应条件
in benzene 12.5 h; Heating;
参考文献
Synthesis, , # 11 p. 1635 - 1638
反应条件
C24H29ClIrN6O2(1+)*C32H12BF24(1-); potassium tert-butylate in deuterated toluene T=110°C; 21 h; Inert atmosphere; Catalytic behavior;
参考文献
Organometallics, , vol. 31, # 21 p. 7500 - 7510
