1,3-二甲基-4-氯-1H-吡唑[3,4-B]并吡啶-5-甲酸乙酯合成路线 （共 8 条）
反应条件
trichlorophosphate 4 h; Heating;
参考文献
Canadian Journal of Chemistry, , vol. 66, # 3 p. 420-428
反应条件
1: 89 percent / 1 h / 120 °C 2: 77 percent / POCl3 / 18 h / 120 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 12, # 15 p. 4089 - 4100
反应条件
1: 89 percent / 1 h / 120 °C 2: 77 percent / POCl3 / 18 h / 120 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 12, # 15 p. 4089 - 4100
反应条件
1: T=160°C; 5 h; 2: With thionyl chloride
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 20, # 7 p. 2340 - 2343
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 13, # 8 p. 1487 - 1490
反应条件
1: 99 percent / potassium hydroxide / H2O; 1,2-dimethoxy-ethane / 18 h / 20 °C 2: SOCl2 / 1 h / 80 °C View Scheme
参考文献
Ochiai, Hiroshi; Ishida, Akiharu; Ohtani, Tazumi; Kusumi, Kensuke; Kishikawa, Katuya; Obata, Takaaki; Nakai, Hisao; Toda, Masaaki
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 1 p. 29 - 32
反应条件
potassium hydroxide in 1,4-dioxane
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 14, # 1 p. 29 - 32
反应条件
in ethanol
3 h; Heating;
参考文献
Khan, Misbahul A.; Pedrotti, Francisco
Monatshefte fuer Chemie, 1982 , vol. 113, p. 123 - 128
