2,3-二甲基-2,3-丁二胺合成路线 （共 38 条）
反应条件
hydrogenchloride; n-butyllithium in cyclohexane; N,N-dimethyl-formamide
参考文献
G.D. Searle and Co.
Patent: US6077850 A1, 2000 ;
反应条件
n-butyllithium; sec-BuLi in tetrahydrofuran; sodium hydroxide; cyclohexane
参考文献
The Procter and Gamble Company
Patent: US5684041 A1, 1997 ;
反应条件
hydrogenchloride; n-butyllithium in tetrahydrofuran; cyclohexane
参考文献
The Procter and Gamble Company
Patent: US5674891 A1, 1997 ;
反应条件
1.1: 78 percent / aq. H2SO4 / methanol / 1 h / 20 °C / pH 3 - 4 2.1: m-chloroperbenzoic acid; NaHCO3 / CH2Cl2 / 1 h / Ice cooling 2.2: 78 percent / aq. NaIO4 / CH2Cl2 View Scheme
参考文献
Hirel, Catherine; Vostrikova, Kira E.; Pecaut, Jacques; Ovcharenko, Victor I.; Rey, Paul
Chemistry - A European Journal, 2001 , vol. 7, # 9 p. 2007 - 2014
反应条件
in diethyl ether; N,N-dimethyl-formamide
参考文献
Eisai Co., Ltd.
Patent: US2002/19531 A1, 2002 ;
US 20020019531 A1
反应条件
iodine in diethyl ether; water
参考文献
Hibi, Shigeki; Hoshino, Yorihisa; Yoshiuchi, Tatsuya; Shin, Kogyoku; Kikuchi, Kouichi; Soejima, Motohiro; Tabata, Mutsuko; Takahashi, Yoshinori; Shibata, Hisashi; Hida, Takayuki; Hirakawa, Tetsuya; Ino, Mitsuhiro
Patent: US2003/78277 A1, 2003 ;
反应条件
hydrogenchloride; n-butyllithium in tetrahydrofuran; hexane; water
参考文献
Rhone-Poulenc Agrochimie
Patent: US5945382 A1, 1999 ;
反应条件
1: 78 percent / aq. H2SO4 / methanol / 1 h / 20 °C / pH 3 - 4
2: 70 percent / m-chloroperbenzoic acid; NaHCO3 / CH2Cl2 / 0.5 h / 6 °C / ice cooling
View Scheme
参考文献
Hirel, Catherine; Vostrikova, Kira E.; Pecaut, Jacques; Ovcharenko, Victor I.; Rey, Paul
Chemistry - A European Journal, 2001 , vol. 7, # 9 p. 2007 - 2014
反应条件
in ethanol
2 h; Heating;
参考文献
Gagnon, Janet L.; Walters, Thomas R.; Zajac, Walter W.; Buzby, John H.
Journal of Organic Chemistry, 1993 , vol. 58, # 24 p. 6712 - 6715
反应条件
potassium carbonate in dimethyl sulfoxide
参考文献
Thackeray, James W.; Coley, Suzanne M.; Cameron, James F.; LaBeaume, Paul J.; Madkour, Ahmad E.; Ongayi, Owendi; Jain, Vipul
Patent: US2012/141939 A1, 2012 ;
