7H-吲哚并[2,3-c]喹啉合成路线 （共 29 条）
反应条件
1: 85 percent / caesium carbonate; 9,9-dimethyl-4,5-(diphenylphosphino)-9H-xanthene / Pd2(dba)3 / dioxane / 16 h / Heating
2: 66 percent / NaOAc*3H2O / PdCl2(PPh3)2 / N,N-dimethyl-acetamide / 0.17 h / 180 °C / microwave irradiation
View Scheme
参考文献
Hostyn, Steven; Maes, Bert U.W.; Van Baelen, Gitte; Gulevskaya, Anna; Meyers, Caroline; Smits, Koen
Tetrahedron, 2006 , vol. 62, # 19 p. 4676 - 4684
反应条件
1.1: 96 percent / Na2CO3 / Pd(PPh3)4 / 1,2-dimethoxy-ethane; H2O / 20 h / Heating
2.1: 89 percent / aq. H2SO4 / ethanol / 24 h / Heating
3.1: NaNO2; HCl / H2O / 1.5 h / 0 °C
3.2: NaN3; NaOAc*3H2O / H2O / 1 h / 0 °C
4.1: 1,2-dichloro-benzene / 3 h / 180 °C
View Scheme
参考文献
Hostyn, Steven; Maes, Bert U.W.; Pieters, Luc; Lemiere, Guy L.F.; Matyus, Peter; Hajos, Gyoergy; Dommisse, Roger A.
Tetrahedron, 2005 , vol. 61, # 6 p. 1571 - 1577
反应条件
1.1: 96 percent / Na2CO3 / Pd(PPh3)4 / 1,2-dimethoxy-ethane; H2O / 20 h / Heating
2.1: 89 percent / aq. H2SO4 / ethanol / 24 h / Heating
3.1: NaNO2; HCl / H2O / 1.5 h / 0 °C
3.2: NaN3; NaOAc*3H2O / H2O / 1 h / 0 °C
4.1: 1,2-dichloro-benzene / 3 h / 180 °C
View Scheme
参考文献
Hostyn, Steven; Maes, Bert U.W.; Pieters, Luc; Lemiere, Guy L.F.; Matyus, Peter; Hajos, Gyoergy; Dommisse, Roger A.
Tetrahedron, 2005 , vol. 61, # 6 p. 1571 - 1577
反应条件
2,2'-azo-bisisobutyronitrile; tri-n-butyl-tin hydride in toluene
48 h; Heating;
参考文献
Kannadasan, Sathananthan; Srinivasan, Panayencheri C.
Synthetic Communications, 2004 , vol. 34, # 7 p. 1325 - 1335
反应条件
1: 70 percent / 5 h / 200 °C
2: 51 percent / sulfuric acid; iodine / benzene; methanol / 48 h / 20 °C / UV-irradiation
View Scheme
参考文献
Dhanabal; Sangeetha; Mohan
Tetrahedron, 2006 , vol. 62, # 26 p. 6258 - 6263
反应条件
1.1: 89 percent / aq. H2SO4 / ethanol / 24 h / Heating
2.1: NaNO2; HCl / H2O / 1.5 h / 0 °C
2.2: NaN3; NaOAc*3H2O / H2O / 1 h / 0 °C
3.1: 1,2-dichloro-benzene / 3 h / 180 °C
View Scheme
参考文献
Hostyn, Steven; Maes, Bert U.W.; Pieters, Luc; Lemiere, Guy L.F.; Matyus, Peter; Hajos, Gyoergy; Dommisse, Roger A.
Tetrahedron, 2005 , vol. 61, # 6 p. 1571 - 1577
反应条件
1.1: NaNO2; HCl / H2O / 1.5 h / 0 °C
1.2: NaN3; NaOAc*3H2O / H2O / 1 h / 0 °C
2.1: 1,2-dichloro-benzene / 3 h / 180 °C
View Scheme
参考文献
Hostyn, Steven; Maes, Bert U.W.; Pieters, Luc; Lemiere, Guy L.F.; Matyus, Peter; Hajos, Gyoergy; Dommisse, Roger A.
Tetrahedron, 2005 , vol. 61, # 6 p. 1571 - 1577
反应条件
in 1,2-dichloro-benzene
T=180°C; 3 h;
参考文献
Hostyn, Steven; Maes, Bert U.W.; Pieters, Luc; Lemiere, Guy L.F.; Matyus, Peter; Hajos, Gyoergy; Dommisse, Roger A.
Tetrahedron, 2005 , vol. 61, # 6 p. 1571 - 1577
反应条件
1: 94 percent / Br2 / dimethylformamide
2: 82 percent / NaOH / benzene
3: 90 percent / NBS; AIBN / CCl4
4: 80 percent / K2CO3 / dimethylformamide / 12 h / 20 °C
5: 33 percent / nBu3SnH; AIBN / toluene / 48 h / Heating
View Scheme
参考文献
Kannadasan, Sathananthan; Srinivasan, Panayencheri C.
Synthetic Communications, 2004 , vol. 34, # 7 p. 1325 - 1335
反应条件
1: 82 percent / NaOH / benzene
2: 90 percent / NBS; AIBN / CCl4
3: 80 percent / K2CO3 / dimethylformamide / 12 h / 20 °C
4: 33 percent / nBu3SnH; AIBN / toluene / 48 h / Heating
View Scheme
参考文献
Kannadasan, Sathananthan; Srinivasan, Panayencheri C.
Synthetic Communications, 2004 , vol. 34, # 7 p. 1325 - 1335
