4-甲基-1-苯基戊烷-1-酮合成路线 （共 23 条）
反应条件
ruthenium trichloride; triphenylphosphine in 1,4-dioxane T=180°C; 40 h;
参考文献
Cho, Chan Sik; Kim, Bok Tae; Lee, Myung Jin; Kim, Tae-Jeong; Shim, Sang Chul
Angewandte Chemie, International Edition, 2001 , vol. 40, # 5 p. 958 - 960
Angewandte Chemie, 2001 , vol. 113, p. 984 - 986
反应条件
sodium hydroxide; [{(η5-C5Me5)IrCl}2(μ-Cl)2] in toluene T=110°C; 17 h;
参考文献
Gnanamgari, Dinakar; Leung, Chin Hin; Schley, Nathan D.; Hilton, Sheena T.; Crabtree, Robert H.
Organic and Biomolecular Chemistry, 2008 , vol. 6, # 23 p. 4442 - 4445
反应条件
K3PO4*3H2O; 5 palladium on charcoal in water T=180°C; 1.5 h; Microwave irradiation;
参考文献
Xu, Guoqiang; Li, Qiong; Feng, Jiange; Liu, Qiang; Zhang, Zuojun; Wang, Xicheng; Zhang, Xiaoyun; Mu, Xindong
ChemSusChem, 2014 , vol. 7, # 1 p. 105 - 109
反应条件
ruthenium trichloride; triphenylphosphine in 1,4-dioxane T=180°C; 40 h;
参考文献
Cho, Chan Sik; Kim, Bok Tae; Lee, Myung Jin; Kim, Tae-Jeong; Shim, Sang Chul
Angewandte Chemie, International Edition, 2001 , vol. 40, # 5 p. 958 - 960
Angewandte Chemie, 2001 , vol. 113, p. 984 - 986
反应条件
potassium tert-butylate in tetrahydrofuran T=0°C;
参考文献
Brown,H.C. et al.
Journal of the American Chemical Society, 1969 , vol. 91, p. 2147 - 2149
反应条件
1: 1,1-dimethyl-2-(1-phenylethylidene)hydrazine With lithium diisopropyl amide in tetrahydrofuran T=0°C; 5.25 h; Inert atmosphere; 2: 2-methyl-1-bromopropane in tetrahydrofuran T=-78 - 20°C; Inert atmosphere; 3: With sulfuric acid; water in diethyl ether 0.5 h; Cooling with ice;
参考文献
Motiwala, Hashim F.; Guelgeze, Belgin; Aube, Jeffrey
Journal of Organic Chemistry, 2012 , vol. 77, # 16 p. 7005 - 7022
反应条件
sulfuric acid in benzene 4 h; Heating;
参考文献
Grison, Claude; Thomas, Antoine; Coutrot, Frederic; Coutrot, Philippe
Tetrahedron, 2003 , vol. 59, # 12 p. 2101 - 2123
反应条件
1: aq. KOH 2: H2 / Raney-Ni View Scheme
参考文献
Ding, Boqiang; Zhang, Zhenfeng; Liu, Yangang; Sugiya, Masashi; Imamoto, Tsuneo; Zhang, Wanbin
Organic Letters, 2013 , vol. 15, # 14 p. 3690 - 3693
反应条件
1.1: POCl3; Et3N / diethyl ether / 1.25 h / -5 - 20 °C 2.1: Et3N / diethyl ether / -20 - 20 °C 3.1: 92 percent / n-BuLi / tetrahydrofuran; hexane / 2 h / -50 - 20 °C 4.1: n-BuLi / tetrahydrofuran; hexane / 0.17 h / -50 °C 4.2: 94 percent / tetrahydrofuran; hexane / 1 h / -50 - 20 °C 5.1: 70 percent / aq. H2SO4 / benzene / 4 h / Heating View Scheme
参考文献
Grison, Claude; Thomas, Antoine; Coutrot, Frederic; Coutrot, Philippe
Tetrahedron, 2003 , vol. 59, # 12 p. 2101 - 2123
反应条件
1.1: Et3N / diethyl ether / -20 - 20 °C 2.1: 92 percent / n-BuLi / tetrahydrofuran; hexane / 2 h / -50 - 20 °C 3.1: n-BuLi / tetrahydrofuran; hexane / 0.17 h / -50 °C 3.2: 94 percent / tetrahydrofuran; hexane / 1 h / -50 - 20 °C 4.1: 70 percent / aq. H2SO4 / benzene / 4 h / Heating View Scheme
参考文献
Grison, Claude; Thomas, Antoine; Coutrot, Frederic; Coutrot, Philippe
Tetrahedron, 2003 , vol. 59, # 12 p. 2101 - 2123
