phosphorus tribromide in chloroform Reduction; 0.75 h; Heating;

1.1: 79 percent / m-CPBA / CHCl3 / 13 h / 25 °C 2.1: 65 percent / KNO3; H2SO4 / 2.5 h / 110 °C 3.1: 88 percent / methanol / 0.5 h / 40 °C 4.1: LTMP / tetrahydrofuran / 1.5 h / -70 °C 4.2: 94 percent / I2 / tetrahydrofuran / 1 h / -70 °C 5.1: 64 percent / PBr3 / CHCl3 / 0.75 h / Heating View Scheme

1.1: 65 percent / KNO3; H2SO4 / 2.5 h / 110 °C 2.1: 88 percent / methanol / 0.5 h / 40 °C 3.1: LTMP / tetrahydrofuran / 1.5 h / -70 °C 3.2: 94 percent / I2 / tetrahydrofuran / 1 h / -70 °C 4.1: 64 percent / PBr3 / CHCl3 / 0.75 h / Heating View Scheme

1.1: LTMP / tetrahydrofuran / 1.5 h / -70 °C 1.2: 94 percent / I2 / tetrahydrofuran / 1 h / -70 °C 2.1: 64 percent / PBr3 / CHCl3 / 0.75 h / Heating View Scheme

1.1: 88 percent / methanol / 0.5 h / 40 °C 2.1: LTMP / tetrahydrofuran / 1.5 h / -70 °C 2.2: 94 percent / I2 / tetrahydrofuran / 1 h / -70 °C 3.1: 64 percent / PBr3 / CHCl3 / 0.75 h / Heating View Scheme

1: 28 percent / KNO3; conc. H2SO4 / 20 h / 80 °C 2: 83 percent / methanol / 0.5 h / 25 - 40 °C 3: 64 percent / PBr3 / CHCl3 / 0.75 h / Heating View Scheme

1: 83 percent / methanol / 0.5 h / 25 - 40 °C 2: 64 percent / PBr3 / CHCl3 / 0.75 h / Heating View Scheme

1.1: TMEDA; BuLi / diethyl ether; hexane / 1 h / -70 °C 1.2: 55 percent / diethyl ether; hexane / 1 h / -70 °C 2.1: 75 percent / hydroxylamine hydrochloride; pyridine / ethanol / 0.75 h / Heating View Scheme