T=10 - 15°C; Hydrogenation;

T=155°C;

T=180°C;

暂无反应条件数据

暂无反应条件数据

Hydrogenation;

1.1: nitric acid / 2 h / Cooling with ice 2.1: palladium 10 on activated carbon; hydrogen; acetic acid / 3 h / 20 °C / 3000.3 Torr 2.2: 4 h / 3000.3 Torr 3.1: pyridine / 1 h / 20 °C 4.1: thionyl chloride / nitromethane / 1 h / Cooling with ice 5.1: AlCl3, aluminium chloride / nitromethane / 0.5 h / 20 °C 5.2: Cooling with ice View Scheme

1.1: hydrazine hydrate / diethylene glycol / 0.5 h / 20 °C 1.2: 120 - 215 °C 2.1: methanesulfonic acid / 0.5 h / 90 °C / Inert atmosphere 3.1: hydrazine hydrate / diethylene glycol / 0.5 h / 20 °C 3.2: 120 - 215 °C 4.1: AlCl3, aluminium chloride / tetrachloroethane, 1,1,2,2- / 20 °C / Cooling with ice 5.1: hydrazine hydrate / diethylene glycol / 0.5 h / 20 °C 5.2: 120 - 215 °C 6.1: sulfuric acid / Reflux 7.1: palladium 10 on activated carbon / triglyme (triethylene glycol dimethyl ether) / 4 h / 240 °C / Inert atmosphere 8.1: methanesulfonic acid / 0.5 h / 90 °C / Inert atmosphere 9.1: n-butyllithium; N-cyclohexyl-N-isopropylamine / tetrahydrofuran; hexane / -78 °C / Inert atmosphere 9.2: 1 h / -78 °C / Inert atmosphere 10.1: palladium 10 on activated carbon / triglyme (triethylene glycol dimethyl ether) / 4 h / 240 °C / Inert atmosphere 11.1: diisobutylaluminium hydride / hexane; toluene / 1 h / -78 °C / Inert atmosphere 11.2: Inert atmosphere 12.1: methanesulfonic acid / dichloromethane / 0.5 h / 20 °C / Cooling with ice View Scheme

1.1: hydrazine hydrate / diethylene glycol / 0.5 h / 20 °C 1.2: 120 - 215 °C 2.1: methanesulfonic acid / 0.5 h / 90 °C / Inert atmosphere 3.1: hydrazine hydrate / diethylene glycol / 0.5 h / 20 °C 3.2: 120 - 215 °C View Scheme

1.1: hydrazine hydrate / diethylene glycol / 0.5 h / 20 °C 1.2: 120 - 215 °C 2.1: methanesulfonic acid / 0.5 h / 90 °C / Inert atmosphere 3.1: hydrazine hydrate / diethylene glycol / 0.5 h / 20 °C 3.2: 120 - 215 °C 4.1: AlCl3, aluminium chloride / tetrachloroethane, 1,1,2,2- / 20 °C / Cooling with ice 5.1: hydrazine hydrate / diethylene glycol / 0.5 h / 20 °C 5.2: 120 - 215 °C 6.1: sulfuric acid / Reflux 7.1: palladium 10 on activated carbon / triglyme (triethylene glycol dimethyl ether) / 4 h / 240 °C / Inert atmosphere 8.1: methanesulfonic acid / 0.5 h / 90 °C / Inert atmosphere View Scheme