2,7-二羟基-4-甲基喹啉合成路线 （共 9 条）
反应条件
sulfuric acid; sodium nitrite 1) H2O, 0 deg C, 2) 10 min, reflux; Yield given. Multistep reaction;
参考文献
Journal of Organic Chemistry, , vol. 56, # 3 p. 980 - 983
反应条件
bismuth(III) chloride T=75°C; Pechmann condensation; 1 h;
参考文献
Synthesis, , # 8 art. no. M08304SS, p. 1231 - 1233
反应条件
sulfuric acid T=70 - 100°C; 1.5 h;
参考文献
Deshmukh; Dhongade-Desai, Savita; Chavan
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2005 , vol. 44, # 8 p. 1659 - 1662
反应条件
hydrogen bromide; acetic acid 75 h; Reflux;
参考文献
Priya, Nivedita; Gupta, Anjali; Chand, Karam; Singh, Prabhjot; Kathuria, Abha; Raj, Hanumantharao G.; Parmar, Virinder S.; Sharma, Sunil K.
Bioorganic and Medicinal Chemistry, 2010 , vol. 18, # 11 p. 4085 - 4094
反应条件
2: NaNO2, H2SO4 / H2O View Scheme
参考文献
Tetrahedron Letters, , vol. 40, # 24 p. 4505 - 4506
反应条件
acetic acid Substitution; 3 h; Heating;
参考文献
Abd El-Aal; Koraierm
Journal of the Chinese Chemical Society, 2000 , vol. 47, # 2 p. 389 - 395
参考文献
Journal of Organic Chemistry, , vol. 56, # 3 p. 980 - 983
反应条件
1: 74 percent / dioxane / Heating 2: 68.78 percent / H2SO4 / 1.5 h / 70 - 100 °C View Scheme
参考文献
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, , vol. 44, # 8 p. 1659 - 1662
反应条件
1: 72 percent / K2CO3 / acetone / 5 h / Heating 2: 70 percent / N,N-diethylaniline / 3 h / Heating 3: 90 percent / CH3COONa / 1 h / Heating 4: 70 percent / Br2, acetic acid / 0.5 h / Ambient temperature 5: 43 percent / 5percent KOH / ethanol / 2 h / Heating 6: 56 percent / K2CO3 / acetone / 3 h / Heating View Scheme
参考文献
Chilin; Rodighiero; Pastorini; Guiotto
Journal of Organic Chemistry, 1991 , vol. 56, # 3 p. 980 - 983
