1: 72 percent / NaI / butan-2-one / 18 h / Heating 2: 90 percent / H2, Et3N / 5percent Pd/C / methanol / 5 h / 22 °C / 760 Torr 3: 0.4N HCl / 1.) 95 deg C, 90 min; 2.) RT, 30 min 4: pyridine / 20 h / 20 °C View Scheme

1: 72 percent / NaI / butan-2-one / 18 h / Heating 2: 90 percent / H2, Et3N / 5percent Pd/C / methanol / 5 h / 22 °C / 760 Torr 3: 0.4N HCl / 1.) 95 deg C, 90 min; 2.) RT, 30 min 4: pyridine / 20 h / 20 °C 5: 65 percent / CF3SO2OSiMe3, hexamethyldisilazane / CH2Cl2 / 20 h / Ambient temperature 6: 97 percent / CH3ONa / methanol / Ambient temperature View Scheme