tetrakis(triphenylphosphine) palladium(0) in toluene Stille Cross Coupling; 20 h; Inert atmosphere;

tetrakis(triphenylphosphine) palladium(0); potassium carbonate in ethylene glycol dimethyl ether; water T=100°C; Suzuki-Miyaura cross-coupling; 8 h; Inert atmosphere;

bis-triphenylphosphine-palladium(II) chloride in tetrahydrofuran 20 h; Heating;

1: With hydrogenchloride; tin(ll) chloride in ethanol T=20°C; 72 h; Inert atmosphere; 2: With potassium hydroxide in water T=-25°C; Inert atmosphere;

1: hydrogenchloride; SnCl2·2H2O / ethanol; water / 18 h / 20 °C 2: methanol / 2 h / 70 °C / Inert atmosphere 3: N-bromosuccinmide / tetrahydrofuran / -78 - 20 °C / Inert atmosphere; Cooling with acetone-dry ice View Scheme