2-溴-5-三氟甲氧基苯酚合成路线 （共 3 条）
反应条件
bromine in dichloromethane T=5 - 10°C; 2 h;
参考文献
WO2005/23806 A2, ;
Page/Page column 57 ;
WO 2005/023806 A2
反应条件
nBu4Br3 in methanol; dichloromethane T=20°C;
参考文献
Tetrahedron Letters, , vol. 52, # 25 p. 3226 - 3227
反应条件
1: 2-bromo-5-(trifluoromethyloxy)phenol With sodium hydroxide in water; toluene
T=1 - 10°C; 0.333333 h;
2: dimethyl sulfate With tetrabutylammomium bromide in water; toluene
T=12 - 15°C;
参考文献
Hodgetts, Kevin J.; John, Stanly; Moorcroft, Neil; Shutske, Greg; Kaiser, Bernd; Yamaguchi, Yasuchika; Ge, Ping; Horvath, Raymond F.
Patent: US2005/70542 A1, 2005 ;
Location in patent: Page/Page column 29-30 ;
