potassium phosphate; copper(l) iodide; N-methyl-2-(methylamino)ethylamine in toluene 24 h; RefluxInert atmosphere;

tetramethyl-ammonium fluoride in tetrahydrofuran T=20°C; 1 h;

1: sodium ethanolate / ethanol / 13.5 h / -5 - 0 °C 2: dirhodium tetraacetate / toluene / |Inert atmosphere; |Reflux 3: potassium phosphate; copper(l) iodide; N-methyl-2-(methylamino)ethylamine / toluene / 24 h / |Reflux; |Inert atmosphere View Scheme

1: dirhodium tetraacetate / toluene / |Inert atmosphere; |Reflux 2: potassium phosphate; copper(l) iodide; N-methyl-2-(methylamino)ethylamine / toluene / 24 h / |Reflux; |Inert atmosphere View Scheme

copper in dichloromethane 24 h; Ambient temperature;

acetic acid; zinc(II) chloride 0.583333 h; Heating; Mechanism;