N-羟基甲基-N-甲基甲酰胺合成路线 （共 3 条）
反应条件
hydrogenchloride; phosphorus trichoride 1.) glac. CH3COOH, 30 min, reflux, 2.) 30 min, reflux; Yield given. Multistep reaction;
参考文献
Tyka, Roman; Haegele, Gerhard
Synthesis, 1984 , # 3 p. 218 - 219
反应条件
thionyl chloride in ethylene glycol dimethyl ether
参考文献
Beecham Group Limited
Patent: US4427689 A1, 1984 ;
反应条件
sodium hydroxide
T=0°C; 0.5 h;
参考文献
Gate; Threadgill; Stevens; Chubb; Vickers; Langdon; Hickman; Gescher
Journal of Medicinal Chemistry, 1986 , vol. 29, # 6 p. 1046 - 1052
